Literature DB >> 25156763

Sleep and respiratory physiology in adults.

Mudiaga Sowho1, Jason Amatoury2, Jason P Kirkness1, Susheel P Patil3.   

Abstract

Respiration during sleep is determined by metabolic demand; respiratory drive is determined by a central respiratory generator. Changes in pharyngeal dilator muscle tone resulting in increased upper airway resistance and collapsibility contribute to hypoventilation. Relative hypotonia of respiratory muscles, body posture changes, and altered ventilatory control result in additional physiologic changes contributing to hypoventilation. This article reviews mechanisms of central control of respiration and normal upper and lower airway physiology. Understanding sleep-related changes in respiratory physiology will help in developing new therapies to prevent hypoventilation in susceptible populations.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Control of breathing; Hypoventilation; Lower airway; Respiratory physiology; Sleep effects; Upper airway

Mesh：

Year:  2014        PMID： 25156763     DOI： 10.1016/j.ccm.2014.06.002

Source DB:  PubMed          Journal:  Clin Chest Med        ISSN： 0272-5231            Impact factor:   2.878


  14 in total

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Authors:  Marcelo P Rodrigues; Carolina M Vissoci; Samuel P Rosa; Sandra B C Negreiros
Journal:  Open Respir Med J       Date:  2017-05-29

9.  Drug-induced sleep endoscopy-directed adenotonsillectomy in pediatric obstructive sleep apnea with small tonsils.

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Journal:  PLoS One       Date:  2019-02-22       Impact factor: 3.240

10.  Calcium Imaging Analysis of Cellular Responses to Hypercapnia and Hypoxia in the NTS of Newborn Rat Brainstem Preparation.

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