| Literature DB >> 2515524 |
E A Runhaar1, J P Neijt, J J Holthuis, D de Vos.
Abstract
The bioavailability of two altretamine preparations was studied in a randomized cross-over design. The two preparations were compared with a third in a parallel design. Dissolution differences between the preparations were observed, which could give rise to differences in bioavailability caused by the extensive first-pass effect of altretamine. The in vivo data showed a trend to differences in bioavailability.Entities:
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Year: 1989 PMID： 2515524 DOI： 10.1007/bf01959414
Source DB: PubMed Journal: Pharm Weekbl Sci ISSN： 0167-6555