Literature DB >> 2515428

Expression of the dnaN and dnaQ genes of Escherichia coli is inducible by mitomycin C.

M Kaasch1, J Kaasch, A Quiñones.   

Abstract

The dnaN and dnaQ genes encode the beta subunit and the epsilon subunit of the DNA polymerase III holoenzyme. Using translational fusions to lacZ we found that DNA damage caused by mitomycin C induces expression of the dnaA and dnaQ genes. This induction was not observed in lexA and recA mutants which block the induction of the SOS response, suggesting a relationship between the mechanism(s) of genetic control of DNA polymerase III holoenzyme and the SOS regulatory network. Nevertheless, there is evidence that the mitomycin C induction of dnaN and dnaQ is not a simple lexA-regulated process, because nalidixic acid (an excellent SOS inducer) does not increase dnaN and dnaQ gene expression, and the time course of induction is abnormally slow.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2515428     DOI： 10.1007/bf00261175

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  50 in total

1.  Escherichia coli gene induction by alkylation treatment.

Authors:  M R Volkert; D C Nguyen; K C Beard
Journal:  Genetics       Date:  1986-01       Impact factor: 4.562

2.  Proofreading by DNA polymerase III of Escherichia coli depends on cooperative interaction of the polymerase and exonuclease subunits.

Authors:  H Maki; A Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

Review 3.  Adaptive response of Escherichia coli to alkylation damage.

Authors:  M R Volkert
Journal:  Environ Mol Mutagen       Date:  1988       Impact factor: 3.216

4.  Cross-linking and repair of DNA in sensitive and resistant strains of E. coli treated with nitrogen mustard.

Authors:  K W Kohn; N H Steigbigel; C L Spears
Journal:  Proc Natl Acad Sci U S A       Date:  1965-05       Impact factor: 11.205

5.  Sequence analysis of the Escherichia coli dnaE gene.

Authors:  H G Tomasiewicz; C S McHenry
Journal:  J Bacteriol       Date:  1987-12       Impact factor: 3.490

6.  Discoordinate gene expression in the dnaA-dnaN operon of Escherichia coli.

Authors:  A Quiñones; W Messer
Journal:  Mol Gen Genet       Date:  1988-07

Review 7.  Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.

Authors:  E M Witkin
Journal:  Bacteriol Rev       Date:  1976-12

8.  Improved plasmid vectors for the isolation of translational lac gene fusions.

Authors:  N P Minton
Journal:  Gene       Date:  1984-11       Impact factor: 3.688

9.  Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli.

Authors:  A Bagg; C J Kenyon; G C Walker
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

10.  Mutagenesis and repair of DNA damage caused by nitrogen mustard, N,N'-bis(2-chloroethyl)-N-nitrosourea (BCNU), streptozotocin, and mitomycin C in E. coli.

Authors:  R J Fram; J Sullivan; M G Marinus
Journal:  Mutat Res       Date:  1986-11       Impact factor: 2.433
View more
  11 in total

1.  DNA lesions that block DNA replication are responsible for the dnaA induction caused by DNA damage.

Authors:  A Quiñones; W R Jueterbock; W Messer
Journal:  Mol Gen Genet       Date:  1991-12

2.  Isolation of DNA damage-inducible promoters in Escherichia coli: regulation of polB (dinA), dinG, and dinH by LexA repressor.

Authors:  L K Lewis; M E Jenkins; D W Mount
Journal:  J Bacteriol       Date:  1992-05       Impact factor: 3.490

3.  Stationary phase induction of dnaN and recF, two genes of Escherichia coli involved in DNA replication and repair.

Authors:  M Villarroya; I Pérez-Roger; F Macián; M E Armengod
Journal:  EMBO J       Date:  1998-03-16       Impact factor: 11.598

Review 4.  Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda.

Authors:  A Kuzminov
Journal:  Microbiol Mol Biol Rev       Date:  1999-12       Impact factor: 11.056

5.  Expression of the dnaB gene of Escherichia coli is inducible by replication-blocking DNA damage in a recA-independent manner.

Authors:  S Kleinsteuber; A Quiñones
Journal:  Mol Gen Genet       Date:  1995-10-25

6.  DNA polymerase I and the bypassing of RecA dependence of constitutive stable DNA replication in Escherichia coli rnhA mutants.

Authors:  Y Cao; R R Rowland; T Kogoma
Journal:  J Bacteriol       Date:  1993-11       Impact factor: 3.490

7.  Expression of the dnaA gene of Escherichia coli is inducible by DNA damage.

Authors:  A Quiñones; W R Jüterbock; W Messer
Journal:  Mol Gen Genet       Date:  1991-05

8.  Inactivation of DNA proofreading obviates the need for SOS induction in frameshift mutagenesis.

Authors:  R P Fuchs; R L Napolitano
Journal:  Proc Natl Acad Sci U S A       Date:  1998-10-27       Impact factor: 11.205

9.  Inducible transcription of the dnaA gene from Streptomyces lividans 66.

Authors:  J Zakrzewska-Czerwińska; J Nardmann; H Schrempf
Journal:  Mol Gen Genet       Date:  1994-02

10.  Static and Dynamic Factors Limit Chromosomal Replication Complexity in Escherichia coli, Avoiding Dangers of Runaway Overreplication.

Authors:  Sharik R Khan; Tulip Mahaseth; Elena A Kouzminova; Glen E Cronan; Andrei Kuzminov
Journal:  Genetics       Date:  2016-01-22       Impact factor: 4.562
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.