| Literature DB >> 25152509 |
Mazhar Hussain1, Sassan Asgari2.
Abstract
Insects are the most successful group of animals on earth, owing this partly to their very effective immune responses to microbial invasion. These responses mainly include cellular and humoral responses as well as RNA interference (RNAi). Small non-coding RNAs (snRNAs) produced through RNAi are important molecules in the regulation of gene expression in almost all living organisms; contributing to important processes such as development, differentiation, immunity as well as host-microorganism interactions. The main snRNAs produced by the RNAi response include short interfering RNAs, microRNAs and piwi-interacting RNAs. In addition to the host snRNAs, some microorganisms encode snRNAs that affect the dynamics of host-pathogen interactions. In this review, we will discuss the latest developments in regards to the role of microRNA in insect host-pathogen interactions and provide some insights into this rapidly developing area of research.Keywords: Immunity; Insect; Interactions; MicroRNA; Pathogen; Virus
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Year: 2014 PMID： 25152509 DOI： 10.1016/j.jinsphys.2014.08.003
Source DB: PubMed Journal: J Insect Physiol ISSN： 0022-1910 Impact factor: 2.354