David S Logerstedt1, Joseph Zeni2, Lynn Snyder-Mackler2. 1. Department of Physical Therapy, University of Delaware, Newark, DE. Electronic address: davlog@udel.edu. 2. Department of Physical Therapy, University of Delaware, Newark, DE.
Abstract
OBJECTIVE: To quantify the differences in physical impairments and in performance-based measures and patient-reported outcomes in men and women seeking nonoperative management of symptomatic moderate knee osteoarthritis (OA) and those with symptomatic end-stage knee OA scheduled for total knee arthroplasty compared with healthy controls. DESIGN: Cross-sectional analysis of individuals referred to physical therapy, community participants, and subjects from a 2-year longitudinal study. SETTING: University research department. PARTICIPANTS: Cross-sectional analysis of participants (N=289) consisting of a moderate OA group (n=83), a severe OA group (n=143), and a healthy control group (n=63). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Quadriceps strength, timed Up and Go test, stair-climbing test, 6-minute walk test, Knee Outcome Survey-Activities of Daily Living Scale (KOS-ADLS), and Physical Component Summary (PCS) of the Medical Outcomes Study 36-Item Short-Form Health Survey. RESULTS: Women had worse scores than men for physical impairment and performance-based measures (P<.001). In the moderate OA group, women had significantly lower KOS-ADLS (P=.007) and PCS (P=.026) scores than men, with no differences seen between sexes in the other 2 groups for patient-reported measures. CONCLUSIONS: Differences between women and men with knee OA on physical impairments and performance-based measures are not echoed in the differences seen in patient-reported measures. These measures signal different domains of knee function in patients with knee OA and should be used as part of a comprehensive functional evaluation.
OBJECTIVE: To quantify the differences in physical impairments and in performance-based measures and patient-reported outcomes in men and women seeking nonoperative management of symptomatic moderate knee osteoarthritis (OA) and those with symptomatic end-stage knee OA scheduled for total knee arthroplasty compared with healthy controls. DESIGN: Cross-sectional analysis of individuals referred to physical therapy, community participants, and subjects from a 2-year longitudinal study. SETTING: University research department. PARTICIPANTS: Cross-sectional analysis of participants (N=289) consisting of a moderate OA group (n=83), a severe OA group (n=143), and a healthy control group (n=63). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Quadriceps strength, timed Up and Go test, stair-climbing test, 6-minute walk test, Knee Outcome Survey-Activities of Daily Living Scale (KOS-ADLS), and Physical Component Summary (PCS) of the Medical Outcomes Study 36-Item Short-Form Health Survey. RESULTS:Women had worse scores than men for physical impairment and performance-based measures (P<.001). In the moderate OA group, women had significantly lower KOS-ADLS (P=.007) and PCS (P=.026) scores than men, with no differences seen between sexes in the other 2 groups for patient-reported measures. CONCLUSIONS: Differences between women and men with knee OA on physical impairments and performance-based measures are not echoed in the differences seen in patient-reported measures. These measures signal different domains of knee function in patients with knee OA and should be used as part of a comprehensive functional evaluation.
Authors: Ryan L Mizner; Stephanie C Petterson; Jennifer E Stevens; Michael J Axe; Lynn Snyder-Mackler Journal: J Rheumatol Date: 2005-08 Impact factor: 4.666
Authors: Molly B Conroy; C Kent Kwoh; Eswar Krishnan; Michael C Nevitt; Robert Boudreau; Laura D Carbone; Hepei Chen; Tamara B Harris; Anne B Newman; Bret H Goodpaster Journal: Arthritis Care Res (Hoboken) Date: 2012-01 Impact factor: 4.794
Authors: D T Felson; R C Lawrence; P A Dieppe; R Hirsch; C G Helmick; J M Jordan; R S Kington; N E Lane; M C Nevitt; Y Zhang; M Sowers; T McAlindon; T D Spector; A R Poole; S Z Yanovski; G Ateshian; L Sharma; J A Buckwalter; K D Brandt; J F Fries Journal: Ann Intern Med Date: 2000-10-17 Impact factor: 25.391
Authors: Allison M Gustavson; Pamela Wolfe; Jason R Falvey; Donald G Eckhoff; Michael J Toth; Jennifer E Stevens-Lapsley Journal: Arch Phys Med Rehabil Date: 2016-04-08 Impact factor: 3.966
Authors: Luis Carlos Pereira; Claude Schweizer; Sara Moufarrij; Swenn M Krähenbühl; Julien Favre; Gerald Gremion; Lee Ann Applegate; Brigitte M Jolles Journal: Pilot Feasibility Stud Date: 2019-04-22