Kally Yuen1, Susy M Harrigan2, Andrew J Mackinnon3, Meredith G Harris4, Hok Pan Yuen5, Lisa P Henry6, Henry J Jackson7, Helen Herrman8, Patrick D McGorry9. 1. Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: kally.yuen@unimelb.edu.au. 2. Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: susy@unimelb.edu.au. 3. Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: Andrew.Mackinnon@unimelb.edu.au. 4. Queensland Centre for Mental Health Research, School of Population Health, The University of Queensland, Australia. Electronic address: meredith_harris@qcmhr.uq.edu.au. 5. Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: hpy@unimelb.edu.au. 6. Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: lisahenry@fastmail.fm. 7. School of Psychological Sciences, The University of Melbourne, Parkville, Australia. Electronic address: henryjj@unimelb.edu.au. 8. Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: h.herrman@unimelb.edu.au. 9. Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: pmcgorry@unimelb.edu.au.
Abstract
OBJECTIVE: To determine mortality-related estimates and causes of death in young people with first-episode psychosis (FEP), and to identify baseline predictors of mortality. METHOD: Mortality outcomes in 723 young people presenting to an early psychosis service were prospectively ascertained up to 20 years. Predictors of all-cause and unnatural death were investigated using survival techniques. RESULTS: Forty-nine participants died by study end. Most deaths (n=41) occurred within 10 years of service entry. All-cause mortality was 5.5% at 10 years, rising to 8.0% after 20 years. Unnatural death rates at 10 and 20 years were 5.0% and 5.9%, respectively. Three risk factors consistently predicted all-cause mortality and unnatural deaths. CONCLUSION: A substantial proportion of excess mortality was due to non-suicide unnatural death, and, later, natural deaths. This suggests that mental health services should expand their current focus on suicide to incorporate strategies to prevent accidental death and promote healthier lifestyles.
OBJECTIVE: To determine mortality-related estimates and causes of death in young people with first-episode psychosis (FEP), and to identify baseline predictors of mortality. METHOD: Mortality outcomes in 723 young people presenting to an early psychosis service were prospectively ascertained up to 20 years. Predictors of all-cause and unnatural death were investigated using survival techniques. RESULTS: Forty-nine participants died by study end. Most deaths (n=41) occurred within 10 years of service entry. All-cause mortality was 5.5% at 10 years, rising to 8.0% after 20 years. Unnatural death rates at 10 and 20 years were 5.0% and 5.9%, respectively. Three risk factors consistently predicted all-cause mortality and unnatural deaths. CONCLUSION: A substantial proportion of excess mortality was due to non-suicide unnatural death, and, later, natural deaths. This suggests that mental health services should expand their current focus on suicide to incorporate strategies to prevent accidental death and promote healthier lifestyles.
Authors: Michael Schoenbaum; Jason M Sutherland; Andre Chappel; Susan Azrin; Amy B Goldstein; Agnes Rupp; Robert K Heinssen Journal: Schizophr Bull Date: 2017-10-21 Impact factor: 9.306
Authors: Sherry Kit Wa Chan; Stephanie Wing Yan Chan; Herbert H Pang; Kang K Yan; Christy Lai Ming Hui; Wing Chung Chang; Edwin Ho Ming Lee; Eric Yu Hai Chen Journal: JAMA Psychiatry Date: 2018-05-01 Impact factor: 21.596