| Literature DB >> 25151002 |
Elisa Kieback1, Ellen Hilgenberg, Simon Fillatreau.
Abstract
Retrogenic mice provide a unique system for rapidly analyzing the function of genes in the hematopoietic system. Here, we provide a detailed protocol for the production of retrogenic mice expressing genes coding for T cell receptor (TCR) for antigen. This technology should be easy to establish in any laboratory and should allow for a rapid progress in our understanding of the functional roles of TCR repertoires in immunity.Entities:
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Year: 2014 PMID: 25151002 DOI: 10.1007/978-1-4939-1212-4_12
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745