| Literature DB >> 25149597 |
Julie Blatt1, Sherif Farag2, Seth J Corey3, Zafeira Sarrimanolis2, Eugene Muratov2, Denis Fourches2, Alexander Tropsha2, William P Janzen4.
Abstract
Drug repurposing is the use of 'old' drugs for new indications, avoiding the need for time- and cost-intensive toxicity studies. This approach should be particularly attractive for pediatrics, but its use in this population has been limited. One obstacle has been the lack of a comprehensive database of drugs for which there already is at least one indication in children. We describe the development of The Children's Pharmacy Collaborative, which should grow over time, serve as a resource for professionals and families, and stimulate drug-repurposing efforts for a range of pediatric disorders.Entities:
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Year: 2014 PMID: 25149597 PMCID: PMC4578872 DOI: 10.1016/j.drudis.2014.08.003
Source DB: PubMed Journal: Drug Discov Today ISSN: 1359-6446 Impact factor: 7.851