| Literature DB >> 25149370 |
Amanda K Lane1, Chad E Niederhuth, Lexiang Ji, Robert J Schmitz.
Abstract
ENCODE projects exist for many eukaryotes, including humans, but as of yet no defined project exists for plants. A plant ENCODE would be invaluable to the research community and could be more readily produced than its metazoan equivalents by capitalizing on the preexisting infrastructure provided from similar projects. Collecting and normalizing plant epigenomic data for a range of species will facilitate hypothesis generation, cross-species comparisons, annotation of genomes, and an understanding of epigenomic functions throughout plant evolution. Here, we discuss the need for such a project, outline the challenges it faces, and suggest ways forward to build a plant ENCODE.Entities:
Keywords: DNA elements; comparative epigenomics; epigenetics
Mesh:
Year: 2014 PMID: 25149370 PMCID: PMC4463858 DOI: 10.1146/annurev-genet-120213-092443
Source DB: PubMed Journal: Annu Rev Genet ISSN: 0066-4197 Impact factor: 16.830