Literature DB >> 25147049

Biocompatible reactive oxygen species (ROS)-responsive nanoparticles as superior drug delivery vehicles.

Dinglin Zhang1, Yanling Wei, Kai Chen, Xiangjun Zhang, Xiaoqiu Xu, Qing Shi, Songling Han, Xin Chen, Hao Gong, Xiaohui Li, Jianxiang Zhang.   

Abstract

A novel reactive oxygen species (ROS)-responsive nanoplatform can be successfully manufactured from a ROS-triggerable β-cyclodextrin material. Extensive in vitro and in vivo studies validate that this nanoscaled system may serve as a new drug delivery vehicle with well-defined ROS-sensitivity and superior biocompatibility. This nanocarrier can be used for ROS-triggered transport of diverse therapeutics and imaging agents.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  ROS-responsiveness; cyclodextrin; drug delivery; nanomedicine; tumor targeting

Mesh：

Substances：

Year:  2014        PMID： 25147049     DOI： 10.1002/adhm.201400299

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  17 in total

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Review 2.  Applications and perspectives of nanomaterials in novel vaccine development.

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Review 3.  Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems.

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Review 5.  Biomaterial-mediated modification of the local inflammatory environment.

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Review 6.  Reactive-Oxygen-Species-Responsive Drug Delivery Systems: Promises and Challenges.

Authors:  Gurusamy Saravanakumar; Jihoon Kim; Won Jong Kim
Journal:  Adv Sci (Weinh)       Date:  2016-06-08       Impact factor: 16.806

Review 7.  ROS-responsive drug delivery systems.

Authors:  Jing Liang; Bin Liu
Journal:  Bioeng Transl Med       Date:  2016-07-05

Review 8.  Macrocyclic Compounds for Drug and Gene Delivery in Immune-Modulating Therapy.

Authors:  Hongzhen Bai; Jianwei Wang; Zhongbao Li; Guping Tang
Journal:  Int J Mol Sci       Date:  2019-04-28       Impact factor: 5.923

9.  A Multifunctional Nanotherapy for Targeted Treatment of Colon Cancer by Simultaneously Regulating Tumor Microenvironment.

Authors:  Qixiong Zhang; Fuzhong Zhang; Shanshan Li; Renfeng Liu; Taotao Jin; Yin Dou; Zhenhua Zhou; Jianxiang Zhang
Journal:  Theranostics       Date:  2019-05-31       Impact factor: 11.556

10.  A Broad-Spectrum ROS-Eliminating Material for Prevention of Inflammation and Drug-Induced Organ Toxicity.

Authors:  Lanlan Li; Jiawei Guo; Yuquan Wang; Xiaoxing Xiong; Hui Tao; Jin Li; Yi Jia; Houyuan Hu; Jianxiang Zhang
Journal:  Adv Sci (Weinh)       Date:  2018-08-16       Impact factor: 16.806
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