Michael Engelhardt1, Eva Spech2, Hermann Diener3, Hermann Faller4, Matthias Augustin5, Eike S Debus3. 1. Department of Vascular and Endovascular Surgery, Military Hospital Ulm, Germany. 2. Department of Surgery, University Hospital Würzburg, Germany. 3. University Heart Center, Department of Vascular Medicine, University Clinics of Hamburg, Germany. 4. Department of Medical Psychology, Medical Sociology, and Rehabilitation Sciences, University of Würzburg, Germany. 5. Institute for Health Services Research in Dermatology and Nursing, University Clinics of Hamburg, Germany.
Abstract
BACKGROUND: Aim of the study was to validate a newly developed disease-specific quality of life questionnaire (Wuerzburg Wound Score, WWS) in patients with chronic arterial or venous leg ulcers. PATIENTS AND METHODS: In this prospective study 115 patients with vascular disease associated leg ulcer (54 arterial ulcer, 61 venous ulcer) were studied (mean age 66 ± 11 years, 51 % male). All patients completed the WWS at baseline, and after four and 12 weeks. To assess construct validity additionally all patients completed the generic QoL-questionnaires Short Form-36 (SF-36) and Nottingham Health Profile (NHP). Construct validity and responsiveness of the WWS were tested. RESULTS: WWS showed acceptable construct validity versus SF-36 (r = 0.5 - 0.78; P < 0.001) and NHP (r = 0.36 - 0.68; P < 0.001). Responsiveness of the WWS was superior to SF-36 (P < 0.05) and NHP (P = 0.01). Generic as well as disease-specific QoL were more impaired in patients with arterial ulcer. CONCLUSIONS: The WWS is a valid measure of disease-specific QoL in patients with leg ulcers and it is more sensitive than the generic instruments in detecting changes of wound healing over time. Further assessment of the psychometric properties of the WWS with larger patient samples is required before the test can be recommended for use in clinical practice.
BACKGROUND: Aim of the study was to validate a newly developed disease-specific quality of life questionnaire (Wuerzburg Wound Score, WWS) in patients with chronic arterial or venous leg ulcers. PATIENTS AND METHODS: In this prospective study 115 patients with vascular disease associated leg ulcer (54 arterial ulcer, 61 venous ulcer) were studied (mean age 66 ± 11 years, 51 % male). All patients completed the WWS at baseline, and after four and 12 weeks. To assess construct validity additionally all patients completed the generic QoL-questionnaires Short Form-36 (SF-36) and Nottingham Health Profile (NHP). Construct validity and responsiveness of the WWS were tested. RESULTS: WWS showed acceptable construct validity versus SF-36 (r = 0.5 - 0.78; P < 0.001) and NHP (r = 0.36 - 0.68; P < 0.001). Responsiveness of the WWS was superior to SF-36 (P < 0.05) and NHP (P = 0.01). Generic as well as disease-specific QoL were more impaired in patients with arterial ulcer. CONCLUSIONS: The WWS is a valid measure of disease-specific QoL in patients with leg ulcers and it is more sensitive than the generic instruments in detecting changes of wound healing over time. Further assessment of the psychometric properties of the WWS with larger patient samples is required before the test can be recommended for use in clinical practice.
Entities:
Keywords:
Quality of life; Wuerzburg Wound Score; chronic venous insufficiency; critical limb ischaemia; leg ulcer; peripheral arterial disease
Authors: Adriana Lozano-Platonoff; Jose Contreras-Ruiz; Judith Dominguez-Cherit; Andrea Cardenas-Sanchez; Valeria Alvarez-Rivero; Joel A Martínez-Regalado Journal: Int Wound J Date: 2019-11-11 Impact factor: 3.315
Authors: Matthias Augustin; Katrin Baade; Kristina Heyer; Patricia E Price; Katharina Herberger; Thomas Wild; Michael Engelhardt; Eike S Debus Journal: Int Wound J Date: 2017-09-06 Impact factor: 3.315
Authors: Philip Goodney; Samir Shah; Yiyuan David Hu; Bjoern Suckow; Scott Kinlay; David G Armstrong; Patrick Geraghty; Megan Patterson; Matthew Menard; Manesh R Patel; Michael S Conte Journal: J Vasc Surg Date: 2022-01-24 Impact factor: 4.860