Literature DB >> 25144905

Tandem phosphorothioate modifications for DNA adsorption strength and polarity control on gold nanoparticles.

Wenhu Zhou1, Feng Wang, Jinsong Ding, Juewen Liu.   

Abstract

Unmodified DNA was recently used to functionalize gold nanoparticles via DNA base adsorption. Compared to thiolated DNA, however, the application of unmodified DNA is limited by the lack of sequence generality, adsorption polarity control and poor adsorption stability. We report that these problems can be solved using phosphorothioate (PS) DNA. PS DNA binds to gold mainly via the sulfur atom and is thus less sequence dependent. The adsorption affinity is ranked to be thiol > PS > adenine > thymine. Tandem PS improves adsorption strength, allows tunable DNA density, and the resulting conjugates are functional at a low cost.

Entities:  

Keywords:  DNA; adsorption; gold nanoparticles; nanotechnology; phosphorothioate; self-assembly

Mesh:

Substances:

Year:  2014        PMID: 25144905     DOI: 10.1021/am504791b

Source DB:  PubMed          Journal:  ACS Appl Mater Interfaces        ISSN: 1944-8244            Impact factor:   9.229


  8 in total

Review 1.  Quantum dots-DNA bioconjugates: synthesis to applications.

Authors:  Anusuya Banerjee; Thomas Pons; Nicolas Lequeux; Benoit Dubertret
Journal:  Interface Focus       Date:  2016-12-06       Impact factor: 3.906

Review 2.  Discovery of and Insights into DNA "Codes" for Tunable Morphologies of Metal Nanoparticles.

Authors:  Nitya Sai Reddy Satyavolu; Kang Yong Loh; Li Huey Tan; Yi Lu
Journal:  Small       Date:  2019-05-10       Impact factor: 13.281

3.  Effect of Fluorescent Labels on DNA Affinity for Gold Nanoparticles.

Authors:  Anna V Epanchintseva; Ekaterina A Gorbunova; Elena I Ryabchikova; Inna A Pyshnaya; Dmitrii V Pyshnyi
Journal:  Nanomaterials (Basel)       Date:  2021-04-29       Impact factor: 5.076

4.  DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy.

Authors:  Suchetan Pal; Angana Ray; Chrysafis Andreou; Yadong Zhou; Tatini Rakshit; Marek Wlodarczyk; Masatomo Maeda; Ricardo Toledo-Crow; Naxhije Berisha; Jiang Yang; Hsiao-Ting Hsu; Anton Oseledchyk; Jagannath Mondal; Shengli Zou; Moritz F Kircher
Journal:  Nat Commun       Date:  2019-04-26       Impact factor: 14.919

5.  Wavelength-Selective Activation of Photocaged DNAzymes for Metal Ion Sensing in Live Cells.

Authors:  Xiao Xu; Lu Xiao; Chunmei Gu; Jiachen Shang; Yu Xiang
Journal:  ACS Omega       Date:  2021-05-12

Review 6.  Ultrasmall Luminescent Metal Nanoparticles: Surface Engineering Strategies for Biological Targeting and Imaging.

Authors:  Xiaoxi Luo; Jinbin Liu
Journal:  Adv Sci (Weinh)       Date:  2021-11-19       Impact factor: 16.806

Review 7.  DNA interfaces with dimensional materials for biomedical applications.

Authors:  Narges Asefifeyzabadi; Prabhangshu Kumer Das; Avokerie Hillary Onorimuo; Grace Durocher; Mohtashim Hassan Shamsi
Journal:  RSC Adv       Date:  2021-08-23       Impact factor: 4.036

8.  Hairpin-Spherical Nucleic Acids for Diagnosing COVID-19: a Simple Method to Generalize the Conventional PCR for Molecular Assays.

Authors:  Abbas Karami; Masoumeh Hasani; Farid Azizi Jalilian; Razieh Ezati
Journal:  Anal Chem       Date:  2021-06-22       Impact factor: 6.986

  8 in total

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