Literature DB >> 25144558

Synthesis of 1-(2,3-dihydrobenzofuran-3-yl)-methanesulfonohydrazides through insertion of sulfur dioxide.

Yuanyuan An1, Danqing Zheng, Jie Wu.   

Abstract

A three-component reaction of 2-(allyloxy)anilines, sulfur dioxide and hydrazines under mild conditions is developed, which gives rise to 1-(2,3-dihydrobenzofuran-3-yl)-methanesulfonohydrazides in good yields. This radical process involves an intramolecular 5-exo-cyclization and insertion of sulfur dioxide.

Entities:  

Year:  2014        PMID: 25144558     DOI: 10.1039/c4cc05401f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

Review 1.  Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry.

Authors:  Minghao Feng; Bingqing Tang; Steven H Liang; Xuefeng Jiang
Journal:  Curr Top Med Chem       Date:  2016       Impact factor: 3.295

  1 in total

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