Literature DB >> 25142815

Plant secondary metabolites- potent inhibitors of monoamine oxidase isoforms.

Bijo Mathew, Jerad Suresh, Githa E Mathew, Ramamoorthy Parasuraman, Nalakathu Abdulla.   

Abstract

Target of monoamine oxidase inhibitions are considered as the treatment of depressive states and neurodegenerative disorders, including Parkinson’s and Alzheimer’s diseases. Many medicinal chemistry research groups are actively working in this area for the development of most promising selective MAO inhibitors. Many plant isolates also showed remarkable MAO inhibition in recent years. The objective of this review is to identify the major MAO inhibitors secondary metabolites from plants like flavonoids, alkaloids and xanthones class of compounds.

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Year:  2014        PMID: 25142815     DOI: 10.2174/1871524914666140826111930

Source DB:  PubMed          Journal:  Cent Nerv Syst Agents Med Chem        ISSN: 1871-5249


  8 in total

Review 1.  90 years of monoamine oxidase: some progress and some confusion.

Authors:  Keith F Tipton
Journal:  J Neural Transm (Vienna)       Date:  2018-04-10       Impact factor: 3.575

2.  Ex vivo and in vitro inhibitory potential of Kava extract on monoamine oxidase B activity in mice.

Authors:  Bárbara Nunes Krum; Catiuscia Molz de Freitas; Alcindo Busanello; Larissa Finger Schaffer; Roselei Fachinetto
Journal:  J Tradit Complement Med       Date:  2021-07-14

Review 3.  Natural Compounds as Medical Strategies in the Prevention and Treatment of Psychiatric Disorders Seen in Neurological Diseases.

Authors:  Esra Küpeli Akkol; Irem Tatlı Çankaya; Gökçe Şeker Karatoprak; Elif Carpar; Eduardo Sobarzo-Sánchez; Raffaele Capasso
Journal:  Front Pharmacol       Date:  2021-05-13       Impact factor: 5.810

4.  3D-QSAR and in-silico Studies of Natural Products and Related Derivatives as Monoamine Oxidase Inhibitors.

Authors:  Priyanka Dhiman; Neelam Malik; Anurag Khatkar
Journal:  Curr Neuropharmacol       Date:  2018       Impact factor: 7.363

5.  Synthesis, in vitro enzyme activity and molecular docking studies of new benzylamine-sulfonamide derivatives as selective MAO-B inhibitors.

Authors:  Begüm Nurpelin Sağlık; Derya Osmaniye; Ulviye Acar Çevik; Serkan Levent; Betül Kaya Çavuşoğlu; Özlem Atlı Eklioğlu; Yusuf Özkay; Ali Savaş Koparal; Zafer Asım Kaplancıklı
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051

6.  zzm321990 Annurca Apple Polyphenol Extract Affects Acetyl- Cholinesterase and Mono-Amine Oxidase In Vitro Enzyme Activity.

Authors:  Rosarita Nasso; Valentina Pagliara; Stefania D'Angelo; Rosario Rullo; Mariorosario Masullo; Rosaria Arcone
Journal:  Pharmaceuticals (Basel)       Date:  2021-01-14

Review 7.  Role of Plant Derived Alkaloids and Their Mechanism in Neurodegenerative Disorders.

Authors:  Ghulam Hussain; Azhar Rasul; Haseeb Anwar; Nimra Aziz; Aroona Razzaq; Wei Wei; Muhammad Ali; Jiang Li; Xiaomeng Li
Journal:  Int J Biol Sci       Date:  2018-03-09       Impact factor: 6.580

8.  Selective Interactions of O-Methylated Flavonoid Natural Products with Human Monoamine Oxidase-A and -B.

Authors:  Narayan D Chaurasiya; Jacob Midiwo; Pankaj Pandey; Regina N Bwire; Robert J Doerksen; Ilias Muhammad; Babu L Tekwani
Journal:  Molecules       Date:  2020-11-17       Impact factor: 4.411

  8 in total

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