Literature DB >> 25141314

Assessment of presence and grade of activity in ileal Crohn's disease.

Elif Sarıtaş Yüksel1, Serkan Ipek, Firdevs Topal, Gonca Koç, Zehra Akpınar, James C Slaughter, Orhan Oyar, Belkıs Unsal.   

Abstract

BACKGROUND/AIMS: To assess the sensitivity of magnetic resonance enterography (MRE) in the diagnosis of Crohn's disease (CD) activity and correlation between endoscopic and MRE scores in predicting the activity grade.
MATERIALS AND METHODS: Twenty-five ileal CD patients with clinical and biochemical evidence of activation underwent ileocolonoscopy and MRE within 7 days of their application. Simplified endoscopic scoring of CD (SES-CD) and MRE scores was done and compared with each other and other parameters of activation (CRP, leukocyte count, platelet count).
RESULTS: The sensitivity of MRE scoring was found to be 92%; however, the statistical correlation with SES-CD was not significant (p=0.83) for the grading of the activity.
CONCLUSION: MRE scoring is sensitive enough to use in CD activity evaluation; however, it can not be used alone, and it is rather a complementary technique to endoscopy and is especially valuable for patients with extraluminal disease.

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Year:  2014        PMID: 25141314     DOI: 10.5152/tjg.2014.3862

Source DB:  PubMed          Journal:  Turk J Gastroenterol        ISSN: 1300-4948            Impact factor:   1.852


  5 in total

1.  Serum Levels of Lipopolysaccharide and 1,3-β-D-Glucan Refer to the Severity in Patients with Crohn's Disease.

Authors:  Yanmin Guo; Guangxi Zhou; Chong He; Wenjing Yang; Zhenkun He; Zhanju Liu
Journal:  Mediators Inflamm       Date:  2015-05-28       Impact factor: 4.711

2.  Blockade of PLD2 Ameliorates Intestinal Mucosal Inflammation of Inflammatory Bowel Disease.

Authors:  Guangxi Zhou; Lin Yu; Wenjing Yang; Wei Wu; Leilei Fang; Zhanju Liu
Journal:  Mediators Inflamm       Date:  2016-09-18       Impact factor: 4.711

3.  Assessment of Crohn's disease activity by Doppler sonography.

Authors:  Ying Na; Jian Zhou; Xiang-Min Xiao; Wen-Xing Zhang; Hong-Lei Gao; Yang Wang; Xiao-Yan Han; Zuo-Cheng Sun; Hui-Min Xu
Journal:  Saudi Med J       Date:  2017-04       Impact factor: 1.484

Review 4.  A review of magnetic resonance enterography-based indices for quantification of Crohn's disease inflammation.

Authors:  Noa Rozendorn; Marianne Michal Amitai; Rami Abraham Eliakim; Uri Kopylov; Eyal Klang
Journal:  Therap Adv Gastroenterol       Date:  2018-04-13       Impact factor: 4.409

Review 5.  Implementation of the simple endoscopic activity score in crohn's disease.

Authors:  Efstratios Koutroumpakis; Konstantinos H Katsanos
Journal:  Saudi J Gastroenterol       Date:  2016 May-Jun       Impact factor: 2.485

  5 in total

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