Literature DB >> 25141160

Management of scars: updated practical guidelines and use of silicones.

Sylvie Meaume1, Anne Le Pillouer-Prost2, Bertrand Richert3, Diane Roseeuw4, Javid Vadoud5.   

Abstract

Hypertrophic scars and keloids resulting from surgery, burns, trauma and infection can be associated with substantial physical and psychological distress. Various non-invasive and invasive options are currently available for the prevention and treatment of these scars. Recently, an international multidisciplinary group of 24 experts on scar management (dermatologists; plastic and reconstructive surgeons; general surgeons; physical medicine, rehabilitation and burns specialists; psychosocial and behavioural researchers; epidemiologists; beauticians) convened to update a set of practical guidelines for the prevention and treatment of hypertrophic and keloid scars on the basis of the latest published clinical evidence on existing scar management options. Silicone-based products such as sheets and gels are recommended as the gold standard, first-line, non-invasive option for both the prevention and treatment of scars. Other general scar preventative measures include avoiding sun exposure, compression therapy, taping and the use of moisturisers. Invasive treatment options include intralesional injections of corticosteroids and/or 5-fluorouracil, cryotherapy, radiotherapy, laser therapy and surgical excision. All of these options may be used alone or as part of combination therapy. Of utmost importance is the regular re-evaluation of patients every four to eight weeks to evaluate whether additional treatment is warranted. The amount of scar management measures that are applied to each wound depends on the patient's risk of developing a scar and their level of concern about the scar's appearance. The practical advice presented in the current guidelines should be combined with clinical judgement when deciding on the most appropriate scar management measures for an individual patient.

Entities:  

Keywords:  Guidelines; Prevention; Scar; Silicone gel; Silicone sheet; Treatment

Mesh:

Substances:

Year:  2014        PMID: 25141160     DOI: 10.1684/ejd.2014.2356

Source DB:  PubMed          Journal:  Eur J Dermatol        ISSN: 1167-1122            Impact factor:   3.328


  23 in total

1.  An intra-individual surgical wound comparison shows that octenidine-based hydrogel wound dressing ameliorates scar appearance following abdominoplasty.

Authors:  Johannes Matiasek; Philip Kienzl; Lukas W Unger; Christoph Grill; Rupert Koller; Bela R Turk
Journal:  Int Wound J       Date:  2018-06-29       Impact factor: 3.315

2.  Efficacy and Safety of a Novel 100% Silicone Scar Gel Treatment for Early Intervention in Scar Management.

Authors:  David J Goldberg
Journal:  J Clin Aesthet Dermatol       Date:  2016-12-01

3.  Chest wall abscesses due to continuous application of silicone gel sheets for keloid management.

Authors:  Hon-Lok Tang; Keith K Lau; Ramin Sam; Todd S Ing
Journal:  BMJ Case Rep       Date:  2015-04-28

4.  A Randomized, Single-Blind Trial of Clobetasol Propionate 0.05% Cream Under Silicone Dressing Occlusion Versus Intra-Lesional Triamcinolone for Treatment of Keloid.

Authors:  Norazirah Md Nor; Rasimah Ismail; Adawiyah Jamil; Shamsul Azhar Shah; Farah Hani Imran
Journal:  Clin Drug Investig       Date:  2017-03       Impact factor: 2.859

5.  The Use of Silicone Adhesives for Scar Reduction.

Authors:  Benjamin Bleasdale; Simon Finnegan; Kathyryn Murray; Sean Kelly; Steven L Percival
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-07-01       Impact factor: 4.730

6.  Peroxisome proliferator-activated receptor-γ agonist inhibits collagen synthesis in human keloid fibroblasts by suppression of early growth response-1 expression through upregulation of miR-543 expression.

Authors:  Hua-Yu Zhu; Wen-Dong Bai; Hong-Tao Wang; Song-Tao Xie; Ke Tao; Lin-Lin Su; Jia-Qi Liu; Xue-Kang Yang; Jun Li; Yun-Chuan Wang; Ting He; Jun-Tao Han; Da-Hai Hu
Journal:  Am J Cancer Res       Date:  2016-06-01       Impact factor: 6.166

7.  Light emitting diode-red light for reduction of post-surgical scarring: Results from a dose-ranging, split-face, randomized controlled trial.

Authors:  Alana Kurtti; Julie K Nguyen; Jeremy Weedon; Andrew Mamalis; Yi Lai; Natasha Masub; Amaris Geisler; Daniel M Siegel; Jared R Jagdeo
Journal:  J Biophotonics       Date:  2021-05-04       Impact factor: 3.207

8.  A Clinical Evaluation of Efficacy and Safety of Hyaluronan Sponge with Vitamin C Versus Placebo for Scar Reduction.

Authors:  Bardia Amirlak; Monali Mahedia; Nilay Shah
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-07-11

9.  Successful treatment of lipoatrophy with normal saline.

Authors:  Samantha L Margulies; Andrea Morris
Journal:  JAAD Case Rep       Date:  2015-11-25

10.  Targeted killing of myofibroblasts by biosurfactant di-rhamnolipid suggests a therapy against scar formation.

Authors:  Chong Shen; Lifang Jiang; Huawei Shao; Chuangang You; Guoliang Zhang; Sitong Ding; Tingwei Bian; Chunmao Han; Qin Meng
Journal:  Sci Rep       Date:  2016-11-30       Impact factor: 4.379

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.