Literature DB >> 25141022

Enzymatic size control of RNA particles using complementary rolling circle transcription (cRCT) method for efficient siRNA production.

Daehoon Han1, Yongkuk Park, Hyangsu Nam, Jong Bum Lee.   

Abstract

A novel fabrication method for RNA particles (RPs) was developed based on enzymatic polymerization, and the size of the RPs was controlled intentionally by adjusting the RNA polymerase concentration for a variety of potential applications.

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Year:  2014        PMID： 25141022     DOI： 10.1039/c4cc04969a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Multimeric RNAs for efficient RNA-based therapeutics and vaccines.

Authors:  Dajeong Kim; Sangwoo Han; Yoonbin Ji; Sunghyun Moon; Hyangsu Nam; Jong Bum Lee
Journal:  J Control Release       Date:  2022-03-31       Impact factor: 11.467

2.  Generation of siRNA Nanosheets for Efficient RNA Interference.

Authors:  Hyejin Kim; Jae Sung Lee; Jong Bum Lee
Journal:  Sci Rep       Date:  2016-04-28       Impact factor: 4.379

3.  Bubbled RNA-Based Cargo for Boosting RNA Interference.

Authors:  Hyejin Kim; Jaepil Jeong; Dajeong Kim; Gijung Kwak; Sun Hwa Kim; Jong Bum Lee
Journal:  Adv Sci (Weinh)       Date:  2017-03-27       Impact factor: 16.806

4.  Library siRNA-generating RNA nanosponges for gene silencing by complementary rolling circle transcription.

Authors:  Sangwoo Han; Hyejin Kim; Jong Bum Lee
Journal:  Sci Rep       Date:  2017-08-30       Impact factor: 4.379

5.  Shaping Rolling Circle Amplification Products into DNA Nanoparticles by Incorporation of Modified Nucleotides and Their Application to In Vitro and In Vivo Delivery of a Photosensitizer.

Authors:  Kyoung-Ran Kim; Pascal Röthlisberger; Seong Jae Kang; Kihwan Nam; Sangyoup Lee; Marcel Hollenstein; Dae-Ro Ahn
Journal:  Molecules       Date:  2018-07-23       Impact factor: 4.411
  5 in total

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