| Literature DB >> 25140905 |
Iris Chen1, Vanessa Cummings, Jessica M Fogel, Mark A Marzinke, William Clarke, Matthew B Connor, Sam Griffith, Susan Buchbinder, Steven Shoptaw, Carlos Del Rio, Manya Magnus, Sharon Mannheimer, Darrell P Wheeler, Kenneth H Mayer, Beryl A Koblin, Susan H Eshleman.
Abstract
HIV RNA levels are usually high early in HIV infection. In the HPTN 061 study, men were tested for HIV infection every 6 months; 6 (21.4%) of 28 men who acquired HIV infection during the study had low or undetectable HIV RNA at the time of HIV diagnosis. Antiretroviral drugs were not detected at the time of HIV diagnosis. False-negative HIV test results were obtained for 2 men using multiple assays. Antiretroviral drug resistance mutations were detected in HIV from 1 man. Additional studies are needed to identify factors associated with low HIV RNA levels during early HIV infection.Entities:
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Year: 2014 PMID： 25140905 PMCID： PMC4213245 DOI： 10.1097/QAI.0000000000000298
Source DB: PubMed Journal: J Acquir Immune Defic Syndr ISSN： 1525-4135 Impact factor: 3.731