Literature DB >> 25140455

Development and characterization of a resistance spot welding aerosol generator and inhalation exposure system.

Aliakbar Afshari1, Patti C Zeidler-Erdely, Walter McKinney, Bean T Chen, Mark Jackson, Diane Schwegler-Berry, Sherri Friend, Amy Cumpston, Jared L Cumpston, H Donny Leonard, Terence G Meighan, David G Frazer, James M Antonini.   

Abstract

Limited information exists regarding the health risks associated with inhaling aerosols that are generated during resistance spot welding of metals treated with adhesives. Toxicology studies evaluating spot welding aerosols are non-existent. A resistance spot welding aerosol generator and inhalation exposure system was developed. The system was designed by directing strips of sheet metal that were treated with an adhesive to two electrodes of a spot welder. Spot welds were made at a specified distance from each other by a computer-controlled welding gun in a fume collection chamber. Different target aerosol concentrations were maintained within the exposure chamber during a 4-h exposure period. In addition, the exposure system was run in two modes, spark and no spark, which resulted in different chemical profiles and particle size distributions. Complex aerosols were produced that contained both metal particulates and volatile organic compounds (VOCs). Size distribution of the particles was multi-modal. The majority of particles were chain-like agglomerates of ultrafine primary particles. The submicron mode of agglomerated particles accounted for the largest portion of particles in terms of particle number. Metal expulsion during spot welding caused the formation of larger, more spherical particles (spatter). These spatter particles appeared in the micron size mode and accounted for the greatest amount of particles in terms of mass. With this system, it is possible to examine potential mechanisms by which spot welding aerosols can affect health, as well as assess which component of the aerosol may be responsible for adverse health outcomes.

Entities:  

Keywords:  Aerosol generators; fumes; gases; inhalation; resistance spot welding

Mesh:

Substances:

Year:  2014        PMID: 25140455     DOI: 10.3109/08958378.2014.941118

Source DB:  PubMed          Journal:  Inhal Toxicol        ISSN: 0895-8378            Impact factor:   2.724


  5 in total

1.  Neurotoxicity following acute inhalation of aerosols generated during resistance spot weld-bonding of carbon steel.

Authors:  Krishnan Sriram; Amy M Jefferson; Gary X Lin; Aliakbar Afshari; Patti C Zeidler-Erdely; Terence G Meighan; Walter McKinney; Mark Jackson; Amy Cumpston; Jared L Cumpston; Howard D Leonard; David G Frazer; James M Antonini
Journal:  Inhal Toxicol       Date:  2014-10       Impact factor: 2.724

2.  Effects of acute inhalation of aerosols generated during resistance spot welding with mild-steel on pulmonary, vascular and immune responses in rats.

Authors:  Patti C Zeidler-Erdely; Terence G Meighan; Aaron Erdely; Jeffrey S Fedan; Janet A Thompson; Suzan Bilgesu; Stacey Waugh; Stacey Anderson; Nikki B Marshall; Aliakbar Afshari; Walter McKinney; David G Frazer; James M Antonini
Journal:  Inhal Toxicol       Date:  2014-08-20       Impact factor: 2.724

3.  Comparison of cell counting methods in rodent pulmonary toxicity studies: automated and manual protocols and considerations for experimental design.

Authors:  Patti C Zeidler-Erdely; James M Antonini; Terence G Meighan; Shih-Houng Young; Tracy J Eye; Mary Ann Hammer; Aaron Erdely
Journal:  Inhal Toxicol       Date:  2016-06-02       Impact factor: 2.724

4.  Aerosol characterization and pulmonary responses in rats after short-term inhalation of fumes generated during resistance spot welding of galvanized steel.

Authors:  James M Antonini; Aliakbar Afshari; Terence G Meighan; Walter McKinney; Mark Jackson; Diane Schwegler-Berry; Dru A Burns; Ryan F LeBouf; Bean T Chen; Mohammad Shoeb; Patti C Zeidler-Erdely
Journal:  Toxicol Rep       Date:  2017-02-22

5.  Effects of Simultaneous Exposure to Smoking and Welding Fume on Pulmonary Function Tests in Spot Welders.

Authors:  Gholamreza Pouryaghoub; Elham Nazem; Ramin Mehrdad; Maryam Saraei; Sahar Eftekhari
Journal:  Tanaffos       Date:  2021-01
  5 in total

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