Literature DB >> 25139597

A novel approach to the treatment of diabetic foot abscesses - a case series.

A Cahn1, Kleinman Y.   

Abstract

UNLABELLED: Diabetic foot abscesses are an occasional complication of diabetic foot infections usually involving osteomyelitis and significant soft tissue injury. The standard of care for diabetic foot abscesses is the performance of immediate surgical drainage and debridement. However, this therapeutic mode involves more often than not, some extent of minor amputation and bony loss. With the advent of new therapeutic techniques it may be possible to treat diabetic foot abscesses conservatively.
OBJECTIVE: To explore adjunct therapies in the treatment of diabetic foot abscesses in order to avoid extensive surgery, amputation and tissue loss whilst maintaining limb integrity. METHOD AND
RESULTS: Between January 2011 and June 2012, six patients with a diabetic foot abscess and osteomyelitis presented at our diabetic foot clinic. They were treated with topical oxygen and the abscesses were drained using PolyMem® Wic® Silver Rope (PWSR). All patients experienced full recovery and remained disease free during a follow up period of 4-21 months.
CONCLUSION: Amputation and the removal of infected bone had once been considered the sole treatment for diabetic foot osteomyelitis. Multiple case series and accumulation of clinical experience has shown otherwise, and nowadays medical management of osteomyelitis is the preferred treatment in select patients. In our study, we present a case series of patients suffering from diabetic foot abscesses treated non-surgically. Hopefully this series will lay the foundation for further data demonstrating the feasibility of a conservative approach for diabetic foot abscesses, which may overcome the infection without requiring amputation.

Entities:  

Keywords:  amputation; diabetic foot abscess; osteomyelitis; topical oxygen therapy

Mesh:

Substances:

Year:  2014        PMID: 25139597     DOI: 10.12968/jowc.2014.23.8.394

Source DB:  PubMed          Journal:  J Wound Care        ISSN: 0969-0700            Impact factor:   2.072


  5 in total

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2.  Upregulated expression of polycomb protein Ring1 contributes to poor prognosis and accelerated proliferation in human hepatocellular carcinoma.

Authors:  Yicheng Xiong; Baoying Hu; Lixian Wei; Dawei Jiang; Mingyan Zhu
Journal:  Tumour Biol       Date:  2015-07-04

Review 3.  The Anti-Inflammatory and Antibacterial Action of Nanocrystalline Silver and Manuka Honey on the Molecular Alternation of Diabetic Foot Ulcer: A Comprehensive Literature Review.

Authors:  Ka-Kit Tsang; Enid Wai-Yung Kwong; Kevin Y Woo; Tony Shing-Shun To; Joanne Wai-Yee Chung; Thomas Kwok-Shing Wong
Journal:  Evid Based Complement Alternat Med       Date:  2015-07-28       Impact factor: 2.629

4.  A Pilot Randomized, Controlled Study of Nanocrystalline Silver, Manuka Honey, and Conventional Dressing in Healing Diabetic Foot Ulcer.

Authors:  Ka-Kit Tsang; Enid Wai-Yung Kwong; Tony Shing-Shun To; Joanne Wai-Yee Chung; Thomas Kwok-Shing Wong
Journal:  Evid Based Complement Alternat Med       Date:  2017-01-25       Impact factor: 2.629

5.  Methods used in the study, Evaluation of a polyurethane foam dressing impregnated with 3% povidone-iodine (Betafoam) in a rat wound model, led to unreliable results.

Authors:  Linda Ll Benskin
Journal:  Ann Surg Treat Res       Date:  2018-09-28       Impact factor: 1.859

  5 in total

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