Literature DB >> 25139122

Investigation of the MICs of fidaxomicin and other antibiotics against Hungarian Clostridium difficile isolates.

Zsuzsa Eitel1, Gabriella Terhes1, József Sóki1, Elisabeth Nagy1, Edit Urbán2.   

Abstract

The aim of this study was to investigate in vitro activities of fidaxomicin and other antibiotics against 188 Clostridium difficile strains collected from different centers of Hungary. C. difficile isolates showed minimum inhibitory concentration (MIC) range for fidaxomicin of ≤0.008-0.5 mg/L, with a MIC90 of 0.125 mg/L. Only four isolates (2.1%) had 0.5 mg/L MIC to fidaxomicin. The obtained MICs showed identical distribution to those found in the EUCAST database for wild-type strains.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Antibiotic susceptibility; Clostridium difficile; Fidaxomicin

Mesh:

Substances:

Year:  2014        PMID: 25139122     DOI: 10.1016/j.anaerobe.2014.08.002

Source DB:  PubMed          Journal:  Anaerobe        ISSN: 1075-9964            Impact factor:   3.331


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