Literature DB >> 25137455

Serine-threonine kinases in TCR signaling.

María N Navarro1, Doreen A Cantrell2.   

Abstract

T lymphocyte proliferation and differentiation are controlled by signaling pathways initiated by the T cell antigen receptor. Here we explore how key serine-threonine kinases and their substrates mediate T cell signaling and coordinate T cell metabolism to meet the metabolic demands of participating in an immune response.

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Year:  2014        PMID： 25137455      PMCID： PMC6443032          DOI： 10.1038/ni.2941

Source DB:  PubMed          Journal:  Nat Immunol        ISSN： 1529-2908            Impact factor:   25.606


  99 in total

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6.  G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: dependence on plasma membrane translocation and protein kinase Cepsilon.

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Review 9.  Phosphoinositide 3-kinase in T cell activation and survival.

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Authors:  S A Matthews; E Rozengurt; D Cantrell
Journal:  J Exp Med       Date:  2000-06-19       Impact factor: 14.307
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  35 in total

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8.  Engineering γδT cells limits tonic signaling associated with chimeric antigen receptors.

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Journal:  Nat Immunol       Date:  2016-10-24       Impact factor: 25.606
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