Literature DB >> 25136166

Fertility sparing surgery in gynecologic cancer.

P Rema1, Iqbal Ahmed1.   

Abstract

Fertility preservation is one of the major concerns of young patients diagnosed with gynecological cancer. With newer treatment regimens and better surgical techniques, survival rates after cancer treatment have improved, hence preservation of fertility has recently become an important issue in the treatment of gynecological cancers. Fertility sparing surgery may be an option for early-stage cervical cancer with the development of loop excision techniques and radical trachelectomy which allows a radical approach to cervix cancer at the same time preserving the uterus and thus fertility. Fertility preservation is possible in Stage 1 epithelial ovarian cancers, germ cell ovarian tumors, and borderline cancers. Hormonal therapy with progestin agents is effective in early endometrial cancer. In patients desiring future pregnancy, fertility sparing options must be explored before starting treatment for gynecologic cancers.

Entities:  

Keywords:  Fertility preservation; Fertility sparing surgery; Gynecologic cancers; Hormonal therapy

Year:  2014        PMID: 25136166      PMCID: PMC4126943          DOI: 10.1007/s13224-014-0572-x

Source DB:  PubMed          Journal:  J Obstet Gynaecol India        ISSN: 0975-6434


  21 in total

Review 1.  Radical vaginal trachelectomy (Dargent's operation): a critical review of the literature.

Authors:  P Dursun; E LeBlanc; M C Nogueira
Journal:  Eur J Surg Oncol       Date:  2007-01-05       Impact factor: 4.424

Review 2.  Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions: systematic review and meta-analysis.

Authors:  M Kyrgiou; G Koliopoulos; P Martin-Hirsch; M Arbyn; W Prendiville; E Paraskevaidis
Journal:  Lancet       Date:  2006-02-11       Impact factor: 79.321

3.  ACOG Practice Bulletin. Management of adnexal masses.

Authors: 
Journal:  Obstet Gynecol       Date:  2007-07       Impact factor: 7.661

4.  Epithelial ovarian carcinoma: ESMO clinical recommendations for diagnosis, treatment and follow-up.

Authors:  S Aebi; M Castiglione
Journal:  Ann Oncol       Date:  2008-05       Impact factor: 32.976

Review 5.  Fertility-sparing radical abdominal trachelectomy for cervical carcinoma: technique and review of the literature.

Authors:  Nadeem R Abu-Rustum; Yukio Sonoda; Destin Black; Douglas A Levine; Dennis S Chi; Richard R Barakat
Journal:  Gynecol Oncol       Date:  2006-07-11       Impact factor: 5.482

6.  Having children after cancer. A pilot survey of survivors' attitudes and experiences.

Authors:  L R Schover; L A Rybicki; B A Martin; K A Bringelsen
Journal:  Cancer       Date:  1999-08-15       Impact factor: 6.860

7.  Prognostic importance of degree of differentiation and cyst rupture in stage I invasive epithelial ovarian carcinoma.

Authors:  I Vergote; J De Brabanter; A Fyles; K Bertelsen; N Einhorn; P Sevelda; M E Gore; J Kaern; H Verrelst; K Sjövall; D Timmerman; J Vandewalle; M Van Gramberen; C G Tropé
Journal:  Lancet       Date:  2001-01-20       Impact factor: 79.321

Review 8.  Is levonorgestrel intrauterine system effective for treatment of early endometrial cancer? Report of four cases and review of the literature.

Authors:  Kalyan K Dhar; T NeedhiRajan; M Koslowski; Robert P Woolas
Journal:  Gynecol Oncol       Date:  2005-06       Impact factor: 5.482

9.  Intrauterine progesterone treatment of early endometrial cancer.

Authors:  Fredrick J Montz; Robert E Bristow; Alessandro Bovicelli; Rafael Tomacruz; Robert J Kurman
Journal:  Am J Obstet Gynecol       Date:  2002-04       Impact factor: 8.661

Review 10.  Hormonal therapy for the management of grade 1 endometrial adenocarcinoma: a literature review.

Authors:  Pedro T Ramirez; Michael Frumovitz; Diane C Bodurka; Charlotte C Sun; Charles Levenback
Journal:  Gynecol Oncol       Date:  2004-10       Impact factor: 5.482

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