Literature DB >> 25134851

Open versus endovascular repair of abdominal aortic aneurysm: Incidence of cardiovascular events in 632 patients in a department of defense cohort over 6-year follow-up.

Dustin Thomas1, David Anderson1, Edward Hulten2, Fiora McRae1, Shane Ellis1, Jamil A Malik1, Todd C Villines2, Ahmad M Slim3.   

Abstract

BACKGROUND: Abdominal aortic aneurysm (AAA) is common with unacceptably high rates of mortality and morbidity with unknown rates of complications after repair in the Department of Defense (DoD).
METHODS: All patients treated at a DOD or VA clinic or medical facility with a diagnosis of AAA identified by ICD-9 code search were identified by Patient Administration Systems and Biostatistics Activity (PASBA) using the Standard Inpatient Data Record (SIDR) and Composite Ambulatory Patient Encounter Record (CAPER) from January 2006 till December 2011. The primary outcome was death, myocardial infarction (MI), stroke, and cardiac arrhythmia between subjects who underwent endovascular aortic repair (EVAR) or open aortic repair (OAR).
RESULTS: A total of 8314 patients were screened to identify 632 patients who underwent surgical repair of non-ruptured AAA. EVAR was performed in 497 patients (78.6%) and OAR in 135 patients (21.4%). Mortality at 30 days was less common in EVAR patients (1.6% vs. 6.7%, p = 0.004), but was not sustained (16.9% vs. 17.8%, p = 0.797). Mean survival free from mortality was not different between the two groups (EVAR vs. OAR: 6.14 ± 0.13 years vs. 6.11 ± 0.22 years, p = 0.378). The composite endpoint of MI, stroke, arrhythmia, or death was not different between groups at 30 days (EVAR vs. OAR: 12.9% vs. 14.1%, p = 0.774) or in long-term follow-up population (EVAR vs. OAR: 40.6% vs. 31.9%, p = 0.073) though there was a trend toward higher event rates in the EVAR. The composite endpoint of MI, stroke, and arrhythmia occurred in 198 patients (31%).
CONCLUSION: EVAR was associated with lower 30-day mortality rates; however, this benefit was not sustained in longer-term follow-up. There is no difference in the rates of stroke, myocardial infarction, or cardiac arrhythmia at 30 days or in long-term follow-up.
© The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Entities:  

Keywords:  Endovascular; abdominal aortic aneurysm; cardiovascular outcomes; myocardial infarction; open

Mesh:

Year:  2014        PMID: 25134851     DOI: 10.1177/1708538114546207

Source DB:  PubMed          Journal:  Vascular        ISSN: 1708-5381            Impact factor:   1.285


  4 in total

1.  Endovascular Aneurysm Sealing is Associated with Higher Medium-Term Survival than Traditional EVAR.

Authors:  Thomas F X O'Donnell; Jeffrey P Carpenter; John S Lane; Jose Trani; Sajjad Hussain; Christopher Healey; Mahmoud B Malas; Marc L Schermerhorn
Journal:  Ann Vasc Surg       Date:  2019-10-16       Impact factor: 1.466

Review 2.  A clinical and ethical review on late results and benefits after EVAR.

Authors:  Carlo Setacci; Pasqualino Sirignano; Vittorio Fineschi; Paola Frati; Giovanna Ricci; Francesco Speziale
Journal:  Ann Med Surg (Lond)       Date:  2017-02-20

3.  Clinical evaluation of endovascular repair of abdominal aortic aneurysm based on long-term experiences.

Authors:  Piotr Kulig; Krzysztof Lewandowski; Bogusław Rudel; Maciej Chwała; Marek Piwowarczyk; Wojciech Mrowiecki
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2020-03-27       Impact factor: 1.195

4.  Short-term outcomes of endovascular repair of abdominal aortic aneurysm, including ruptured cases.

Authors:  Piotr Kulig; Krzysztof Lewandowski; Bartłomiej Banaś; Piotr Piekorz; Andrzej Kostka; Maciej Zaniewski
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2018-02-07       Impact factor: 1.195

  4 in total

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