Literature DB >> 25132918

Continued evidence for safety of endoscopic retrograde cholangiopancreatography during pregnancy.

Sean Fine1, Joshua Beirne1, Silvia Delgi-Esposti1, Fadlallah Habr1.   

Abstract

AIM: To report the safety of continued use of endoscopic retrograde cholangiopancreatography (ERCP) during pregnancy at various maternal ages.
METHODS: A retrospective chart review of pregnant patients who underwent ERCP at a tertiary academic center was undertaken between 2002 and 2012. Pertinent past medical history and initial presenting laboratory data were collected. Review of the procedure note for each ERCP performed provided documentation of lead shielding, type of sedation, fluoroscopy time, and post-procedure complications. Patients' clinical courses were reviewed until the time of delivery and pregnancy complications with fetal outcomes were examined. Data was stratified based upon the mother's age at the time of ERCP: 18-21, 22-29, and ≥ 30 years of age.
RESULTS: Twenty pregnant patients who underwent ERCP between 2002 and 2012 were identified. The mean age at the time of ERCP was 26.4 years (18-38 years) and the average trimester was the second. The indications for ERCP were choledocholithiasis in 17 patients, gallstone pancreatitis in 2 patients, and cholangitis in 1 patient. The mean fluoroscopy time of ERCP was 3.8 min (0.3-23.6 min). Sphincterotomy was performed in 18 patients with therapeutic intent and not as a prophylactic measure to prevent recurrences. Clinical documentation of use of protective shielding was found in only 8 notes (40%). Post procedure complications were limited to two cases of post-ERCP pancreatitis (10%). Elective cholecystectomy was performed shortly after ERCP in 11 of the pregnant patients. Birth records were available for 16 patients, of which 15 had full-term pregnancies. Cesarean sections were performed in 5 (31%) patients. Term birth weight was greater than 2500 g in all cases except one in which the mother had a known hypercoagulable state.
CONCLUSION: ERCP during pregnancy is both safe and efficacious regardless of maternal age or trimester.

Entities:  

Keywords:  Caesarean section; Cholecystectomy; Choledocholithiasis; Endoscopic retrograde cholangiopancreatography; Pancreatitis; Pregnancy

Year:  2014        PMID: 25132918      PMCID: PMC4133414          DOI: 10.4253/wjge.v6.i8.352

Source DB:  PubMed          Journal:  World J Gastrointest Endosc


  25 in total

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Journal:  Am J Gastroenterol       Date:  2006-01       Impact factor: 10.864

7.  Risk factors for complications after ERCP: a multivariate analysis of 11,497 procedures over 12 years.

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8.  Safety and efficacy of ERCP in pregnancy.

Authors:  Michel Kahaleh; Gary D Hartwell; Kristen O Arseneau; Thomas N Pajewski; Tarun Mullick; Gulkan Isin; Suresh Agarwal; Paul Yeaton
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Authors:  T Hassold; D Chiu
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

10.  Endoscopic retrograde cholangiopancreatography in pregnancy.

Authors:  P A Jamidar; G J Beck; B J Hoffman; G A Lehman; R H Hawes; R M Agrawal; P S Ashok; T J Ravi; J T Cunningham; F Troiano
Journal:  Am J Gastroenterol       Date:  1995-08       Impact factor: 10.864

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