Literature DB >> 25132321

An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes.

Malay Patra1, Andreas Bauman, Cristina Mari, Christiane A Fischer, Olivier Blacque, Daniel Häussinger, Gilles Gasser, Thomas L Mindt.   

Abstract

(89)Zr-based imaging agents hold great promise as novel radio-tracers in nuclear medicine. However, insufficient stability of currently used radiometal complexes in vivo is a safety concern for clinical applications. We herein report the first octadentate bifunctional chelating agent for the development of (89)Zr-labelled (bio)conjugates with improved stability.

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Year:  2014        PMID： 25132321     DOI： 10.1039/c4cc05558f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  39 in total

1.  Macrocycle-Based Hydroxamate Ligands for Complexation and Immunoconjugation of 89Zirconium for Positron Emission Tomography (PET) Imaging.

Authors:  Eszter Boros; Jason P Holland; Nathaniel Kenton; Nicholas Rotile; Peter Caravan
Journal:  Chempluschem       Date:  2016-01-25       Impact factor: 2.863

Review 2.  Progress of Coordination and Utilization of Zirconium-89 for Positron Emission Tomography (PET) Studies.

Authors:  Minh Thanh La; Van Hieu Tran; Hee-Kwon Kim
Journal:  Nucl Med Mol Imaging       Date:  2019-01-29

3.  Investigation of the complexation of natZr(iv) and 89Zr(iv) by hydroxypyridinones for the development of chelators for PET imaging applications.

Authors:  F Guérard; M Beyler; Y-S Lee; R Tripier; J-F Gestin; M W Brechbiel
Journal:  Dalton Trans       Date:  2017-04-05       Impact factor: 4.390

4.  Multifunctional Desferrichrome Analogues as Versatile 89Zr(IV) Chelators for ImmunoPET Probe Development.

Authors:  Casey J Adams; Justin J Wilson; Eszter Boros
Journal:  Mol Pharm       Date:  2017-07-19       Impact factor: 4.939

Review 5.  Chemical aspects of metal ion chelation in the synthesis and application antibody-based radiotracers.

Authors:  Eszter Boros; Jason P Holland
Journal:  J Labelled Comp Radiopharm       Date:  2018-03-12       Impact factor: 1.921

6.  Di-macrocyclic terephthalamide ligands as chelators for the PET radionuclide zirconium-89.

Authors:  Darpan N Pandya; Sylvie Pailloux; David Tatum; Darren Magda; Thaddeus J Wadas
Journal:  Chem Commun (Camb)       Date:  2015-02-11       Impact factor: 6.222

7.  A comprehensively revised strategy that improves the specific activity and long-term stability of clinically relevant 89Zr-immuno-PET agents.

Authors:  Nikunj B Bhatt; Darpan N Pandya; Stephanie Rideout-Danner; Howard D Gage; Frank C Marini; Thaddeus J Wadas
Journal:  Dalton Trans       Date:  2018-09-04       Impact factor: 4.390

8.  Total-Body PET and Highly Stable Chelators Together Enable Meaningful 89Zr-Antibody PET Studies up to 30 Days After Injection.

Authors:  Eric Berg; Herman Gill; Jan Marik; Annie Ogasawara; Simon Williams; Guus van Dongen; Daniëlle Vugts; Simon R Cherry; Alice F Tarantal
Journal:  J Nucl Med       Date:  2019-09-27       Impact factor: 10.057

9.  ImmunoPET: Concept, Design, and Applications.

Authors:  Weijun Wei; Zachary T Rosenkrans; Jianjun Liu; Gang Huang; Quan-Yong Luo; Weibo Cai
Journal:  Chem Rev       Date:  2020-03-23       Impact factor: 60.622

10.  Evaluation of a chloride-based 89Zr isolation strategy using a tributyl phosphate (TBP)-functionalized extraction resin.

Authors:  Stephen A Graves; Christopher Kutyreff; Kendall E Barrett; Reinier Hernandez; Paul A Ellison; Steffen Happel; Eduardo Aluicio-Sarduy; Todd E Barnhart; Robert J Nickles; Jonathan W Engle
Journal:  Nucl Med Biol       Date:  2018-06-18       Impact factor: 2.408
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