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Literature DB >> 2513220

In vivo degradation of noradrenaline by MAO A in locus coeruleus of the rat.

Abstract

Depletion of noradrenaline in locus coeruleus neurons after reserpinization was prevented by clorgyline, a selective inhibitor of MAO A, but not by deprenyl, a selective inhibitor of MAO B. Only MAO A is therefore responsible for the degradation of homoneuronal noradrenaline in locus coeruleus nerve cells.

Entities: Chemical Gene Species

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Year: 1989 PMID： 2513220 DOI： 10.1007/bf01950168

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

16 in total

1. Demonstration of monoamine oxidase type B in serotonergic and type A in noradrenergic neurons in the cat dorsal pontine tegmentum by an improved histochemical technique.

Authors: K Kitahama; R Arai; T Maeda; M Jouvet
Journal: Neurosci Lett Date: 1986-10-30 Impact factor: 3.046

2. Distribution of catechol-O-methyltransferase, histamine N-methyltransferase and monoamine oxidase in specific areas of the rat brain.

Authors: J M Saavedra; M J Brownstein; M Palkovits
Journal: Brain Res Date: 1976-12-10 Impact factor: 3.252

3. Histochemical localisation of monoamine oxidase A and B in rat brain.

Authors: J Willoughby; V Glover; M Sandler
Journal: J Neural Transm Date: 1988 Impact factor: 3.575

4. Localization of distinct monoamine oxidase A and monoamine oxidase B cell populations in human brainstem.

Authors: K N Westlund; R M Denney; R M Rose; C W Abell
Journal: Neuroscience Date: 1988-05 Impact factor: 3.590

5. Cumulative effects of irreversible MAO inhibitors in vivo.

Authors: A E Felner; P C Waldmeier
Journal: Biochem Pharmacol Date: 1979-04-01 Impact factor: 5.858

6. The oxidation of adrenaline and noradrenaline by the two forms of monoamine oxidase from human and rat brain.

Authors: A M O'Carroll; M E Bardsley; K F Tipton
Journal: Neurochem Int Date: 1986 Impact factor: 3.921

7. Topographic atlas of monoamine oxidase-containing neurons in the rat brain studied by an improved histochemical method.

Authors: R Arai; H Kimura; T Maeda
Journal: Neuroscience Date: 1986-11 Impact factor: 3.590

In vivo degradation of noradrenaline by MAO A in locus coeruleus of the rat.

1. Demonstration of monoamine oxidase type B in serotonergic and type A in noradrenergic neurons in the cat dorsal pontine tegmentum by an improved histochemical technique.

2. Distribution of catechol-O-methyltransferase, histamine N-methyltransferase and monoamine oxidase in specific areas of the rat brain.

3. Histochemical localisation of monoamine oxidase A and B in rat brain.

4. Localization of distinct monoamine oxidase A and monoamine oxidase B cell populations in human brainstem.

5. Cumulative effects of irreversible MAO inhibitors in vivo.

6. The oxidation of adrenaline and noradrenaline by the two forms of monoamine oxidase from human and rat brain.

7. Topographic atlas of monoamine oxidase-containing neurons in the rat brain studied by an improved histochemical method.

8. Histochemistry of MAO-A and MAO-B in the locus coeruleus of the Mongolian gerbil.

9. A and B forms of monoamine oxidase within the monoaminergic neurons of the rat brain.

10. Clorgyline and deprenyl insensitive monoamine oxidase in rat brain soluble fraction.

1. Quantitative distribution of rat brain monoamine oxidase A by [14C]clorgyline autoradiography.