Literature DB >> 25131900

Effects of salpingectomy and antituberculosis treatments on fertility results in patients with genital tuberculosis.

Eray Caliskan1, Yigit Cakiroglu, Kenan Sofuoglu, Emek Doger, Munire E Akar, Sabiha O Ozkan.   

Abstract

AIM: The aim of this study was to demonstrate the effects of tubal surgery and antituberculosis treatments in patients with genital tuberculosis.
MATERIAL AND METHODS: A total of 38 infertile women who had been diagnosed with pelvic tuberculosis and who had had laparoscopy and hysteroscopy were recruited into the study. All women with female genital tuberculosis were divided into two groups: group 1 (salpingectomized, n=21) and group 2 (not salpingectomized, n=15). Both of the groups were treated with antitubercular therapy for 6-12 months.
RESULTS: There was no significant difference in level of gonadotrophins used, estradiol levels on human chorionic gonadotrophin day, mean and mature oocytes retrieved, mean embryos transferred, or cancellation and fertilization rates. Only the number of days of stimulation was statistically significantly higher in group 1 compared to group 2 (10.4±2.3 vs 9.2±1.8; P=0.048). Although it did not reach the statistically significant level, clinical pregnancy rate was higher in group 1 (37.5%, 12/32 vs 23.8%, 5/21; P=0.306). Although not statistically significant, number of ongoing pregnancies per embryo transfer, spontaneous abortion rates before 20 weeks of gestation and take-home baby rates were higher in group 1 compared to group 2 (15.5%, 12/77 vs 6.6%, 3/45; P=0.150; 28.1%, 9 vs 23.8%, 5; P=0.600; 9%, 3 vs 0; P=0.160, respectively).
CONCLUSION: Salpingectomy is an option for treatment in patients diagnosed with pelvic tuberculosis and infertility to improve both clinical pregnancy rates and take-home baby rates in patients treated with antituberculosis therapy for 12 months.
© 2014 The Authors. Journal of Obstetrics and Gynaecology Research © 2014 Japan Society of Obstetrics and Gynecology.

Entities:  

Keywords:  endoscopy; infertility; salpingectomy; tuberculosis

Mesh:

Substances:

Year:  2014        PMID: 25131900     DOI: 10.1111/jog.12450

Source DB:  PubMed          Journal:  J Obstet Gynaecol Res        ISSN: 1341-8076            Impact factor:   1.730


  5 in total

1.  Pregnancy after frozen embryo transfer in mycobacterium tuberculous salpingitis: A case report and literature review.

Authors:  Firouzeh Ghaffari; Shokouholsadat Miralaie; Zahra Chekini; Maziar Faridi
Journal:  Int J Reprod Biomed       Date:  2020-06-30

2.  Female genital tuberculosis cases with distinct clinical symptoms: Four case reports.

Authors:  Gonul Aslan; Mahmut Ulger; Seda Tezcan Ulger; Huseyin Durukan; Faik Gurkan Yazici; Gurol Emekdas
Journal:  Int J Reprod Biomed       Date:  2018-01

3.  The combined fixed-dose antituberculous drugs alter some reproductive functions with oxidative stress involvement in wistar rats.

Authors:  O Awodele; A A Momoh; N A Awolola; O E Kale; W O Okunowo
Journal:  Toxicol Rep       Date:  2016-07-19

4.  Lower cumulative live birth rates in cured endometrial tuberculosis patients after one ART cycle including all subsequent frozen-thaw cycles: A matched-pair study.

Authors:  Ming-Mei Lin; Wan Yang; Xiao-Guo Du; Xue-Ling Song; Jie Qiao; Rong Li
Journal:  Eur J Obstet Gynecol Reprod Biol X       Date:  2019-11-22

5.  A woman with disseminated tuberculosis experienced preterm delivery, fallopian tube pregnancy, and delivered successfully following in vitro fertilization: a case report.

Authors:  Ming Cheng; Tao Yuan; Ying Liu
Journal:  BMC Pregnancy Childbirth       Date:  2021-01-07       Impact factor: 3.007

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.