| Literature DB >> 25131025 |
S Gullo-Neto1, A Vontobel Padoin1, J E Queiroz de Carvalho2, R Wendling3, M A Traesel4, L Kroth4, C Miranda5, A Colombo Balestro5, R Siqueira5, B Chao Lisot5, S Lima5, C Corá Mottin1, D Saitovitch6.
Abstract
Metabolic surgery for the treatment of type 2 diabetes mellitus (T2DM) in patients not morbidly obese (BMI <35) has been widely studied. Taking into account that ∼12% of pancreas transplants are performed in patients with T2DM, our goal was to evaluate the impact of metabolic surgery on the management of obese patients with T2DM on waiting lists for a pancreas transplant. We performed a Roux-en-Y gastrointestinal bypass in 5 patients with insulin-dependent T2DM who were candidates for pancreas after kidney transplant and with a BMI <35. Three patients became insulin independent by the end of the first year while the other 2 reduced their insulin requirements by 70%. Furthermore, all patients achieved improved control of lipid levels. We concluded that the surgery was effective in controlling blood glucose and lipid metabolism in these obese T2DM kidney transplant recipients. In this population, a pancreas transplant, along with its associated morbidity, may be avoided.Entities:
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Year: 2014 PMID： 25131025 DOI： 10.1016/j.transproceed.2014.05.005
Source DB: PubMed Journal: Transplant Proc ISSN： 0041-1345 Impact factor: 1.066