| Literature DB >> 25130746 |
Shun Suda1, Kazunari Watanabe, Yuki Tanaka, Kazuhiro Watanabe, Rie Tanaka, Jun Ogihara, Toyohiko Ariga, Tomomi Hosono-Fukao, Takashi Hosono, Taiichiro Seki.
Abstract
To identify the molecular target of diallyl trisulfide (DATS) in human leukemic cell line U937, we examined modification of thiol group(s) of cellular proteins by the redox 2D PAGE. A unique protein spot appeared by DATS treatment was identified to be heat shock protein 27 (HSP27). Hsp27 is suggested to be one of the molecular target of DATS in U937.Entities:
Keywords: U937; diagonal gel electrophoresis; diallyl trisulfide; garlic; heat shock protein 27 (HSP27)
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Year: 2014 PMID： 25130746 DOI： 10.1080/09168451.2014.921563
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043