Literature DB >> 2513055

Computer control of anticoagulant dose for therapeutic management.

P J Ryan1, M Gilbert, P E Rose.   

Abstract

OBJECTIVE: To improve the standard of managing anticoagulant treatment and provide a basis for therapeutic quality control.
DESIGN: Implementation of a comprehensive computerised system for decision support.
SETTING: Three anticoagulation clinics in South Warwickshire.
SUBJECTS: Patients in South Warwickshire receiving anticoagulant treatment from September 1988 to March 1989. MAIN OUTCOME MEASURE: International normalised ratio was measured and recorded at each visit.
RESULTS: 688 Patients' visits were analysed statistically, and a 38% improvement was achieved in the results of international normalised ratios falling within the recommended therapeutic ranges of the British Society for Haematology.
CONCLUSIONS: The implementation of a computerised anticoagulation support system resulted in better management of patients. The system provides a basis for uniform management of treatment and a common platform for national or international trials.

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Year:  1989        PMID: 2513055      PMCID: PMC1838076          DOI: 10.1136/bmj.299.6709.1207

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  6 in total

1.  Survey of prothrombin time in National External Quality Assessment Scheme exercises (1980-87).

Authors:  L Poller; D A Taberner; J M Thomson; K V Darby
Journal:  J Clin Pathol       Date:  1988-04       Impact factor: 3.411

2.  Computer dosing in anticoagulant clinics--the way forward?

Authors:  P J Wyld; D West; T H Wilson
Journal:  Clin Lab Haematol       Date:  1988

3.  United Kingdom external quality assessment in blood coagulation: the first 21 years.

Authors:  L Poller
Journal:  J Clin Pathol       Date:  1989-01       Impact factor: 3.411

4.  Quality of oral anticoagulant therapy.

Authors: 
Journal:  Clin Lab Haematol       Date:  1986

5.  Computer assisted management of warfarin treatment.

Authors:  R Wilson; A H James
Journal:  Br Med J (Clin Res Ed)       Date:  1984-08-18

6.  Assessment of therapeutic control of anticoagulation.

Authors:  A Copplestone; S Roath
Journal:  Acta Haematol       Date:  1984       Impact factor: 2.195

  6 in total
  22 in total

1.  Computer control of anticoagulant dose.

Authors:  P E Rose; M Gilbert
Journal:  BMJ       Date:  1990-02-03

Review 2.  Monitoring in chronic disease: a rational approach.

Authors:  Paul Glasziou; Les Irwig; David Mant
Journal:  BMJ       Date:  2005-03-19

Review 3.  Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Authors:  Walter Ageno; Alexander S Gallus; Ann Wittkowsky; Mark Crowther; Elaine M Hylek; Gualtiero Palareti
Journal:  Chest       Date:  2012-02       Impact factor: 9.410

Review 4.  Oral anticoagulation control: the European perspective.

Authors:  David A Fitzmaurice
Journal:  J Thromb Thrombolysis       Date:  2006-02       Impact factor: 2.300

5.  Managing the increased workload in anticoagulant clinics. Computerised decision support is valuable.

Authors:  D A Fitzmaurice; P E Rose; M Gilbert
Journal:  BMJ       Date:  1996-05-11

6.  Audit of anticoagulant therapy.

Authors:  P E Rose
Journal:  J Clin Pathol       Date:  1996-01       Impact factor: 3.411

7.  Where should oral anticoagulation monitoring take place?

Authors:  F D Hobbs; D A Fitzmaurice
Journal:  Br J Gen Pract       Date:  1997-08       Impact factor: 5.386

8.  Computer control of anticoagulant dose.

Authors: 
Journal:  BMJ       Date:  1989-12-16

9.  A Bayesian dose-individualization method for warfarin.

Authors:  Daniel F B Wright; Stephen B Duffull
Journal:  Clin Pharmacokinet       Date:  2013-01       Impact factor: 6.447

10.  Prospective comparative study of computer programs used for management of warfarin.

Authors:  L Poller; D Wright; M Rowlands
Journal:  J Clin Pathol       Date:  1993-04       Impact factor: 3.411

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