Ruth O Teh1, Ngaire M Kerse2, Elizabeth M Robinson3, Gillian A Whalley4, Martin J Connolly5, Robert N Doughty6. 1. Department of General Practice and Primary Health Care, University of Auckland. Electronic address: r.teh@auckland.ac.nz. 2. Department of General Practice and Primary Health Care, University of Auckland. 3. Department of Epidemiology and Biostatistics, University of Auckland. 4. Faculty of Social and Health Sciences, Unitec Institute of Technology. 5. Freemasons' Department of Geriatric Medicine, University of Auckland. 6. Dept of Medicine and National Institute for Health Innovation, University of Auckland.
Abstract
BACKGROUND: Abnormalities of cardiac structure and function are common in a wide range of populations including those with and without established clinical cardiovascular disease (CVD). This study reports the prevalence of left ventricular hypertrophy (LVH), the four patterns of LV geometry and establishes clinical characteristics and five-year outcomes of each group in people of advanced age. METHOD: A study conducted in general practices and Māori Health Services in three New Zealand North Island locations. One hundred participants had a full clinical echocardiogram performed and analysed in 2008 by one experienced cardiologist blinded to the participant's clinical history. RESULTS: Two-thirds of the participants had CVD. Thirty-two participants had echocardiographic LVH. Those with LVH had higher left atrial area [median (IQR) 26.4cm(2) (10.9) vs. 22.0cm(2) (7.0), p<0.01] and E/e' [median (IQR) 13 (6.8) vs.10.8 (4.1), p=0.01] than those without LVH. Of those with LVH, 10 demonstrated concentric hypertrophy (CH) and 22 eccentric hypertrophy (EH); 12 concentric remodelling (CR) and 40 normal geometry (NG). Both CR and EH were independently associated with higher risk of all-cause mortality (p<0.01) and hospital admissions (p<0.05) than those with NG. Those with EH also had a higher risk of CVD events (p=0.029). CONCLUSIONS: Despite a high prevalence of CVD and hypertension in this sample, half had normal LV geometry. Concentric remodelling and eccentric hypertrophy were associated with higher mortality and adverse CVD outcomes in people of advanced age.
BACKGROUND: Abnormalities of cardiac structure and function are common in a wide range of populations including those with and without established clinical cardiovascular disease (CVD). This study reports the prevalence of left ventricular hypertrophy (LVH), the four patterns of LV geometry and establishes clinical characteristics and five-year outcomes of each group in people of advanced age. METHOD: A study conducted in general practices and Māori Health Services in three New Zealand North Island locations. One hundred participants had a full clinical echocardiogram performed and analysed in 2008 by one experienced cardiologist blinded to the participant's clinical history. RESULTS: Two-thirds of the participants had CVD. Thirty-two participants had echocardiographic LVH. Those with LVH had higher left atrial area [median (IQR) 26.4cm(2) (10.9) vs. 22.0cm(2) (7.0), p<0.01] and E/e' [median (IQR) 13 (6.8) vs.10.8 (4.1), p=0.01] than those without LVH. Of those with LVH, 10 demonstrated concentric hypertrophy (CH) and 22 eccentric hypertrophy (EH); 12 concentric remodelling (CR) and 40 normal geometry (NG). Both CR and EH were independently associated with higher risk of all-cause mortality (p<0.01) and hospital admissions (p<0.05) than those with NG. Those with EH also had a higher risk of CVD events (p=0.029). CONCLUSIONS: Despite a high prevalence of CVD and hypertension in this sample, half had normal LV geometry. Concentric remodelling and eccentric hypertrophy were associated with higher mortality and adverse CVD outcomes in people of advanced age.
Authors: Dragan B Djordjević; Ivan S Tasić; Svetlana I Kostić; Bojana N Stamenković; Aleksandar D Djordjević; Dragan B Lović Journal: Clin Cardiol Date: 2017-12-16 Impact factor: 2.882
Authors: Floran Sahiti; Caroline Morbach; Vladimir Cejka; Judith Albert; Felizitas A Eichner; Götz Gelbrich; Peter U Heuschmann; Stefan Störk Journal: Front Cardiovasc Med Date: 2021-06-11
Authors: Roberto de Castro Meirelles de Almeida; Antonio José Lagoeiro Jorge; Maria Luiza Garcia Rosa; Adson Renato Leite; Dayse Mary S Correia; Evandro Tinoco Mesquita; Sergio Chermont; Jocemir Ronaldo Lugon; Wolney de Andrade Martins Journal: Arq Bras Cardiol Date: 2020-01 Impact factor: 2.000