Literature DB >> 25129439

Relationship between IL-10 expression and prognosis in patients with primary breast cancer.

Ying Li1, Ping Gao, Junlan Yang, Haiming Yu, Yanyun Zhu, Wen Si.   

Abstract

This retrospective study was designed to investigate the relationship between the expression of IL-10, CD4, CD8, and FOXP3 and clinicopathological features and prognosis in breast cancer patients. The expression of IL-10, CD4, CD8, and FOXP3 was detected by immunohistochemistry. Staining intensity of only IL-10 was associated with disease-free survival and distance disease-free survival (P<0.05). Staining density of IL-10 in stromal cells was associated with overall survival and distance disease-free survival (P<0.05). IL-10 expression levels might be used as a prognostic indicator for the recurrence, metastasis, and survival of breast cancer patients.

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Year:  2014        PMID： 25129439     DOI： 10.1007/s13277-014-2249-6

Source DB:  PubMed          Journal:  Tumour Biol        ISSN： 1010-4283


  18 in total

1.  Interleukin-10 ablation promotes tumor development, growth, and metastasis.

Authors:  Takashi Tanikawa; Cailin Moira Wilke; Ilona Kryczek; Grace Y Chen; John Kao; Gabriel Núñez; Weiping Zou
Journal:  Cancer Res       Date:  2011-11-28       Impact factor: 12.701

2.  Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer.

Authors:  Sahar M A Mahmoud; Emma Claire Paish; Desmond G Powe; R Douglas Macmillan; Matthew J Grainge; Andrew H S Lee; Ian O Ellis; Andrew R Green
Journal:  J Clin Oncol       Date:  2011-04-11       Impact factor: 44.544

Review 3.  Regulatory T cells and breast cancer: implications for immunopathogenesis.

Authors:  Maria Angelica Ehara Watanabe; Julie Massayo Maeda Oda; Marla Karine Amarante; Julio Cesar Voltarelli
Journal:  Cancer Metastasis Rev       Date:  2010-12       Impact factor: 9.264

Review 4.  Biology of interleukin-10.

Authors:  Robert Sabat; Gerald Grütz; Katarzyna Warszawska; Stefan Kirsch; Ellen Witte; Kerstin Wolk; Jens Geginat
Journal:  Cytokine Growth Factor Rev       Date:  2010-11-05       Impact factor: 7.638

5.  IL-10 promotes tumor aggressiveness via upregulation of CIP2A transcription in lung adenocarcinoma.

Authors:  Wen-Wei Sung; Yao-Chen Wang; Po-Lin Lin; Ya-Wen Cheng; Chih-Yi Chen; Tzu-Chin Wu; Huei Lee
Journal:  Clin Cancer Res       Date:  2013-06-06       Impact factor: 12.531

6.  The prognostic role of tumor-infiltrating CD4 and CD8 T lymphocytes in breast cancer.

Authors:  Rafal Matkowski; Iwona Gisterek; Agnieszka Halon; Aleksandra Lacko; Krzysztof Szewczyk; Urszula Staszek; Marek Pudelko; Bartlomiej Szynglarewicz; Jolanta Szelachowska; Andrzej Zolnierek; Jan Kornafel
Journal:  Anticancer Res       Date:  2009-07       Impact factor: 2.480

Review 7.  Cancer-related inflammation.

Authors:  Juliana Candido; Thorsten Hagemann
Journal:  J Clin Immunol       Date:  2012-12-09       Impact factor: 8.317

Review 8.  Immune infiltration in human tumors: a prognostic factor that should not be ignored.

Authors:  F Pagès; J Galon; M-C Dieu-Nosjean; E Tartour; C Sautès-Fridman; W-H Fridman
Journal:  Oncogene       Date:  2009-11-30       Impact factor: 9.867

9.  Concentration of interleukin-6 (IL-6), interleukin-8 (IL-8) and interleukin-10 (IL-10) in blood serum of breast cancer patients.

Authors:  L Kozłowski; I Zakrzewska; P Tokajuk; M Z Wojtukiewicz
Journal:  Rocz Akad Med Bialymst       Date:  2003

10.  Interleukin-10 gene transfer inhibits murine mammary tumors and elevates nitric oxide.

Authors:  N Kundu; R Dorsey; M J Jackson; P Guiterrez; K Wilson; S Fu; K Ramanujam; E Thomas; A M Fulton
Journal:  Int J Cancer       Date:  1998-05-29       Impact factor: 7.396
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  6 in total

1.  A Survey on the Role of Interleukin-10 in Breast Cancer: A Narrative.

Authors:  Elnaz Sheikhpour; Parisa Noorbakhsh; Elnaz Foroughi; Soudabeh Farahnak; Rezvan Nasiri; Hossein Neamatzadeh
Journal:  Rep Biochem Mol Biol       Date:  2018-10

2.  Association of Elevated Expression Levels of COL4A1 in Stromal Cells with an Immunosuppressive Tumor Microenvironment in Low-Grade Glioma, Pancreatic Adenocarcinoma, Skin Cutaneous Melanoma, and Stomach Adenocarcinoma.

Authors:  Hyo-Jae Shin; Minchan Gil; Im-Soon Lee
Journal:  J Pers Med       Date:  2022-03-28

3.  A panel containing PD-1, IL-2Rα, IL-10, and CA15-3 as a biomarker to discriminate breast cancer from benign breast disease.

Authors:  Chao Liu; Bing Sun; Bin Xu; Xiangying Meng; Lan Li; Yang Cong; Jiannan Liu; Qian Wang; Liang Xuan; Qibin Song; Shikai Wu
Journal:  Cancer Manag Res       Date:  2018-06-26       Impact factor: 3.989

4.  Diagnostic value of PD-1 mRNA expression combined with breast ultrasound in breast cancer patients.

Authors:  Jianhua Fang; Yi Shao; Jiezhi Su; Ying Wan; Lingyun Bao; Wei Wang; Fanlei Kong
Journal:  Ther Clin Risk Manag       Date:  2018-08-28       Impact factor: 2.423

5.  Studying the Effect of Garlic Consumption and Endurance Training on Serum Levels of Some Pro-and Anti-inflammatory Cytokines in Female Mice with Breast Cancer - A Randomized Trial.

Authors:  Mansour Enayatjazi; Fahimeh Esfarjani; Jalil Reisi; Seyed Jamal Moshtaghian
Journal:  Int J Prev Med       Date:  2022-03-12

6.  Benefits in radical mastectomy protocol: a randomized trial evaluating the use of regional anesthesia.

Authors:  Marcio Matsumoto; Eva M Flores; Pedro P Kimachi; Flavia V Gouveia; Mayra A Kuroki; Alfredo C S D Barros; Marcelo M C Sampaio; Felipe E M Andrade; João Valverde; Eduardo F Abrantes; Claudia M Simões; Rosana L Pagano; Raquel C R Martinez
Journal:  Sci Rep       Date:  2018-05-18       Impact factor: 4.379
  6 in total

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