Aslam Ejaz1, Gaya Spolverato2, Yuhree Kim2, Rebecca Dodson2, Jason K Sicklick3, Henry A Pitt4, Keith D Lillemoe5, John L Cameron2, Timothy M Pawlik6. 1. Department of Surgery, Johns Hopkins Hospital, Baltimore, MD; Department of Surgery, University of Illinois Hospital and Health Sciences Center, Chicago, IL. 2. Department of Surgery, Johns Hopkins Hospital, Baltimore, MD. 3. Department of Surgery, University of California San Diego School of Medicine, La Jolla, CA. 4. Department of Surgery, Temple University School of Medicine, Philadelphia, PA. 5. Department of Surgery, The Massachusetts General Hospital, Harvard Medical School, Boston, MA. 6. Department of Surgery, Johns Hopkins Hospital, Baltimore, MD. Electronic address: tpawlik1@jhmi.edu.
Abstract
BACKGROUND: Data on the effect of bile duct injuries (BDI) on health-related quality of life (HRQOL) are not well defined. We sought to assess long-term HRQOL after BDI repair in a large cohort of patients spanning a 23-year period. STUDY DESIGN: We identified and mailed HRQOL questionnaires to all patients treated for major BDI after laparoscopic cholecystectomy between January 1, 1990 and December 31, 2012 at Johns Hopkins Hospital. RESULTS: We identified 167 patients alive at the time of the study who met the inclusion criteria. Median age at BDI was 42 years (interquartile range 31 to 54 years); the majority of patients were female (n = 131 [78.4%]) and of white race (n = 137 [83.0%]). Most patients had Bismuth level 2 (n = 56 [33.7%]) or Bismuth level 3 (n = 40 [24.1%]) BDI. Surgical repair most commonly involved a Roux-en-Y hepaticojejunostomy (n = 142 [86.1%]). Sixty-two patients (37.1%) responded to the HRQOL questionnaire. Median follow-up was 169 months (interquartile range 125 to 222 months). At the time of BDI, mental health was most affected, with patients commonly reporting a depressed mood (49.2%) or low energy level (40.0%). These symptoms improved significantly after definitive repair (both p < 0.05). Limitations in physical activity and general health remained unchanged before and after surgical repair (both p > 0.05). CONCLUSIONS: Mental health concerns were more commonplace vs physical or general health issues among patients with BDI followed long term. Optimal multidisciplinary management of BDI can help restore HRQOL to preinjury levels.
BACKGROUND: Data on the effect of bile duct injuries (BDI) on health-related quality of life (HRQOL) are not well defined. We sought to assess long-term HRQOL after BDI repair in a large cohort of patients spanning a 23-year period. STUDY DESIGN: We identified and mailed HRQOL questionnaires to all patients treated for major BDI after laparoscopic cholecystectomy between January 1, 1990 and December 31, 2012 at Johns Hopkins Hospital. RESULTS: We identified 167 patients alive at the time of the study who met the inclusion criteria. Median age at BDI was 42 years (interquartile range 31 to 54 years); the majority of patients were female (n = 131 [78.4%]) and of white race (n = 137 [83.0%]). Most patients had Bismuth level 2 (n = 56 [33.7%]) or Bismuth level 3 (n = 40 [24.1%]) BDI. Surgical repair most commonly involved a Roux-en-Y hepaticojejunostomy (n = 142 [86.1%]). Sixty-two patients (37.1%) responded to the HRQOL questionnaire. Median follow-up was 169 months (interquartile range 125 to 222 months). At the time of BDI, mental health was most affected, with patients commonly reporting a depressed mood (49.2%) or low energy level (40.0%). These symptoms improved significantly after definitive repair (both p < 0.05). Limitations in physical activity and general health remained unchanged before and after surgical repair (both p > 0.05). CONCLUSIONS: Mental health concerns were more commonplace vs physical or general health issues among patients with BDI followed long term. Optimal multidisciplinary management of BDI can help restore HRQOL to preinjury levels.
Authors: Victor Lopez-Lopez; Javier Maupoey; Rafael López-Andujar; Emilio Ramos; Kristel Mils; Pedro Antonio Martinez; Andres Valdivieso; Marina Garcés-Albir; Luis Sabater; Luis Díez Valladares; Sergio Annese Pérez; Benito Flores; Roberto Brusadin; Asunción López Conesa; Valentin Cayuela; Sagrario Martinez Cortijo; Sandra Paterna; Alejando Serrablo; Santiago Sánchez-Cabús; Antonio González Gil; Jose Antonio González Masía; Carmelo Loinaz; Jose Luis Lucena; Patricia Pastor; Cristina Garcia-Zamora; Alicia Calero; Juan Valiente; Antonio Minguillon; Fernando Rotellar; Jose Manuel Ramia; Cándido Alcazar; Javier Aguilo; Jose Cutillas; Christoph Kuemmerli; Jose A Ruiperez-Valiente; Ricardo Robles-Campos Journal: J Gastrointest Surg Date: 2022-07-05 Impact factor: 3.267