| Literature DB >> 25127395 |
Akihiro Tai1, Mei Aburada, Hideyuki Ito.
Abstract
A single-step synthesis of 3-O-ethyl-l-ascorbic acid was performed without the induction of protecting groups. Sodium l-ascorbate reacted with ethyl bromide in DMSO to give 3-O-ethylascorbic acid in a yield of 51.0%. 3-O-Ethylascorbic acid enhanced dibutyryl cyclic AMP-induced neurite outgrowth in PC12 cells.Entities:
Keywords: 3-O-ethylascorbic acid; PC12 cells; neurite outgrowth; single-step synthesis
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Year: 2014 PMID： 25127395 DOI： 10.1080/09168451.2014.946396
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043