Literature DB >> 25127371

Epilepsy, comorbid conditions in Canadian children: analysis of cross-sectional data from cycle 3 of the National Longitudinal Study of Children and Youth.

Asuri N Prasad1, Jorge G Burneo2, Bradley Corbett2.   

Abstract

PURPOSE: The purpose of this study was to analyze national survey data to provide estimates of prevalence of epilepsy and associated developmental disabilities and comorbid conditions.
METHODS: We analyzed data from Cycle 3 of Canada's National Longitudinal Survey of Children and Youth. The NLSCY captured, socio-demographic information, as well as age, sex, education, ethnicity, household income, chronic health related conditions from birth to 15 years old. The main survey question intended to identify "epilepsy", "cerebral palsy", "intellectual disability", "learning disability", and "emotional and nervous difficulties" in the population of children surveyed. Prevalence was based on the national cross-sectional sample and used 1000 bootstrap weights to account for survey design factors.
RESULTS: Cycle 3 of the NLSCY had the largest number of patients with diagnosed epilepsy. Prevalence figures (n/1000) for epilepsy and cerebral palsy (EPI_CP), epilepsy and intellectual disability (EPI_ID), epilepsy and learning disability (EPI_LD), and epilepsy and emotional nervous difficulties (EPI_EMO_NERV) were 1.1, 1.17, 2.58 and 1.34 respectively. Amongst children with epilepsy, 43.17% reported the presence of one or more of the above comorbid conditions.
CONCLUSION: These results provide an initial prevalence estimate of comorbid conditions with epilepsy in Canadian children. In a high proportion of children with epilepsy, the PMK had reported at least one comorbid disorder. These findings carry implications for health care utilization and long-term outcomes. We discuss methodological aspects related to the ascertainment of epilepsy in both surveys, and to the validity and implications of our findings.
Copyright © 2014 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Cerebral palsy; Children; Comorbid; Epilepsy; Learning disability; Population studies

Mesh:

Year:  2014        PMID: 25127371     DOI: 10.1016/j.seizure.2014.07.012

Source DB:  PubMed          Journal:  Seizure        ISSN: 1059-1311            Impact factor:   3.184


  4 in total

1.  Spatial cognition following early-life seizures in rats: Performance deficits are dependent on task demands.

Authors:  Jeremy M Barry; Chengju Tian; Anthony Spinella; Matias Page; Gregory L Holmes
Journal:  Epilepsy Behav       Date:  2016-05-04       Impact factor: 2.937

Review 2.  Effect of Seizures on the Developing Brain and Cognition.

Authors:  Gregory L Holmes
Journal:  Semin Pediatr Neurol       Date:  2016-05-24       Impact factor: 1.636

Review 3.  Sex Differences in the Epilepsies and Associated Comorbidities: Implications for Use and Development of Pharmacotherapies.

Authors:  Catherine A Christian; Doodipala Samba Reddy; Jamie Maguire; Patrick A Forcelli
Journal:  Pharmacol Rev       Date:  2020-10       Impact factor: 25.468

4.  The Clinical Research Landscape of Pediatric Drug-Resistant Epilepsy.

Authors:  K Julia Kaal; Magda Aguiar; Mark Harrison; Patrick J McDonald; Judy Illes
Journal:  J Child Neurol       Date:  2020-06-16       Impact factor: 1.987

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.