Literature DB >> 25126988

Copper as a magic bullet for targeted microbial killing.

Jennifer S Cavet1.   

Abstract

The innate toxicity of copper can be exploited as an antimicrobial. In this issue of Chemistry & Biology Festa and colleagues report the use of QBP, a prochelator form of the metal-chelate 8-hydroxyquinolone, which allows for targeted copper-dependent microbial killing at sites of infection.
Copyright © 2014 Elsevier Ltd. All rights reserved.

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Year:  2014        PMID: 25126988     DOI: 10.1016/j.chembiol.2014.07.011

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  2 in total

1.  Stimulus-Responsive Prochelators for Manipulating Cellular Metals.

Authors:  Qin Wang; Katherine J Franz
Journal:  Acc Chem Res       Date:  2016-10-17       Impact factor: 22.384

Review 2.  The Yin and Yang of copper during infection.

Authors:  Angelique N Besold; Edward M Culbertson; Valeria C Culotta
Journal:  J Biol Inorg Chem       Date:  2016-01-20       Impact factor: 3.358

  2 in total

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