| Literature DB >> 25126777 |
Valérie Borde1, Michael Lichten2.
Abstract
Initiation of meiotic recombination by DNA double-strand break formation is temporally coordinated with replication. Murakami and Keeney show that this coordination requires recruitment of the Dbf4-dependent kinase to the replication fork by the conserved TIM-TIPIN complex. The same mechanism may regulate other important replication-associated processes.Entities:
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Year: 2014 PMID： 25126777 DOI： 10.1016/j.cell.2014.07.029
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582