Carole L Marcus1, Joel Traylor1, Sarah N Biggs2, Robin S Roberts3, Gillian M Nixon4, Indra Narang5, Rakesh Bhattacharjee6, Margot J Davey4, Rosemary S C Horne2, Maureen Cheshire5, K Jeremy Gibbons5, Joanne Dix3, Elizabeth Asztalos7, Lex W Doyle8, Gillian F Opie9, Judy D'ilario3, Lorrie Costantini3, Ruth Bradford1, Barbara Schmidt10. 1. Department of Pediatrics, Sleep Center, Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA; 2. The Ritchie Centre and Department of Paediatrics, Monash University, Melbourne, Victoria, Australia; 3. Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada; 4. The Ritchie Centre and Department of Paediatrics, Monash University, Melbourne, Victoria, Australia; ; Melbourne Children's Sleep Centre, Monash Children's Hospital, Monash Health, Melbourne, Victoria, Australia; 5. Division of Respiratory Medicine, Hospital for Sick Children, Toronto, University of Toronto, Ontario, Canada; 6. Section of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, University of Chicago, Chicago, IL; 7. Department of Pediatrics, University of Toronto, Ontario, Canada; 8. Department of Obstetrics and Gynaecology, the Royal Women's Hospital, University of Melbourne, Parkville, Victoria, Australia, and Clinical Sciences, Murdoch Childrens Research Institute, Parkville, Victoria, Australia; 9. Mercy Hospital for Women, Heidelberg, and Department of Obstetrics and Gynaecology, University of Melbourne, Victoria, Australia; 10. Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada; ; Division of Neonatology, Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA.
Abstract
STUDY OBJECTIVES: Although unattended ambulatory polysomnography (PSG) is frequently performed in adults, few studies have been performed in children. The objective of this study was to evaluate the feasibility of comprehensive, ambulatory PSG, including electroencephalography, in school-aged children in the home environment. METHODS: A total of 201 children, born premature with birth weights of 500-1,250 grams, currently aged 5-12 years and living in Canada and Australia, underwent unattended ambulatory PSG. RESULTS: PSG was initially technically satisfactory in 183 (91%) cases. Fourteen studies were satisfactory when repeated, resulting in an overall satisfactory rate of 197 (98%). Artifact-free signals were obtained for ≥ 75% of recording time in more than 92% of subjects, with the exception of nasal pressure, which was satisfactory for ≥ 75% of recording time in only 67% of subjects. However, thermistry signals were satisfactory for ≥ 75% of recording time in 92% of subjects, and some measure of airflow was present for ≥ 75% of recording time in 96% of subjects. Children slept very well, with a long total sleep time (534 ± 73 [mean ± SD] minutes), high sleep efficiency (92% ± 5%), and low arousal index (9 ± 3/h). Parents and children reported a high rate of satisfaction with the study. CONCLUSIONS: This large, international study has shown that comprehensive, unattended, ambulatory PSG is feasible, technically adequate and well-tolerated in school-aged children when performed under research conditions. Further studies regarding the cost efficacy of this approach, and generalizability of the findings to a clinical population, are warranted.
STUDY OBJECTIVES: Although unattended ambulatory polysomnography (PSG) is frequently performed in adults, few studies have been performed in children. The objective of this study was to evaluate the feasibility of comprehensive, ambulatory PSG, including electroencephalography, in school-aged children in the home environment. METHODS: A total of 201 children, born premature with birth weights of 500-1,250 grams, currently aged 5-12 years and living in Canada and Australia, underwent unattended ambulatory PSG. RESULTS: PSG was initially technically satisfactory in 183 (91%) cases. Fourteen studies were satisfactory when repeated, resulting in an overall satisfactory rate of 197 (98%). Artifact-free signals were obtained for ≥ 75% of recording time in more than 92% of subjects, with the exception of nasal pressure, which was satisfactory for ≥ 75% of recording time in only 67% of subjects. However, thermistry signals were satisfactory for ≥ 75% of recording time in 92% of subjects, and some measure of airflow was present for ≥ 75% of recording time in 96% of subjects. Children slept very well, with a long total sleep time (534 ± 73 [mean ± SD] minutes), high sleep efficiency (92% ± 5%), and low arousal index (9 ± 3/h). Parents and children reported a high rate of satisfaction with the study. CONCLUSIONS: This large, international study has shown that comprehensive, unattended, ambulatory PSG is feasible, technically adequate and well-tolerated in school-aged children when performed under research conditions. Further studies regarding the cost efficacy of this approach, and generalizability of the findings to a clinical population, are warranted.
Entities:
Keywords:
ambulatory; child; home; polysomnography; sleep study
Authors: Carol L Rosen; Emma K Larkin; H Lester Kirchner; Judith L Emancipator; Sarah F Bivins; Susan A Surovec; Richard J Martin; Susan Redline Journal: J Pediatr Date: 2003-04 Impact factor: 4.406
Authors: Barbara Schmidt; Peter J Anderson; Lex W Doyle; Deborah Dewey; Ruth E Grunau; Elizabeth V Asztalos; Peter G Davis; Win Tin; Diane Moddemann; Alfonso Solimano; Arne Ohlsson; Keith J Barrington; Robin S Roberts Journal: JAMA Date: 2012-01-18 Impact factor: 56.272
Authors: Barbara Schmidt; Robin S Roberts; Peter Davis; Lex W Doyle; Keith J Barrington; Arne Ohlsson; Alfonso Solimano; Win Tin Journal: N Engl J Med Date: 2007-11-08 Impact factor: 91.245
Authors: Nancy A Collop; W McDowell Anderson; Brian Boehlecke; David Claman; Rochelle Goldberg; Daniel J Gottlieb; David Hudgel; Michael Sateia; Richard Schwab Journal: J Clin Sleep Med Date: 2007-12-15 Impact factor: 4.062
Authors: Christopher M Cielo; Lourdes M DelRosso; Ignacio E Tapia; Sarah N Biggs; Gillian M Nixon; Lisa J Meltzer; Joel Traylor; Ji Young Kim; Carole L Marcus Journal: Sleep Med Date: 2016-03-15 Impact factor: 3.492
Authors: Ahmed I Masoud; Pallavi P Patwari; Pranshu A Adavadkar; Henry Arantes; Chang Park; David W Carley Journal: J Clin Sleep Med Date: 2019-05-15 Impact factor: 4.062
Authors: Carole L Marcus; Lisa J Meltzer; Robin S Roberts; Joel Traylor; Joanne Dix; Judy D'ilario; Elizabeth Asztalos; Gillian Opie; Lex W Doyle; Sarah N Biggs; Gillian M Nixon; Indra Narang; Rakesh Bhattacharjee; Margot Davey; Rosemary S C Horne; Maureen Cheshire; Jeremy Gibbons; Lorrie Costantini; Ruth Bradford; Barbara Schmidt Journal: Am J Respir Crit Care Med Date: 2014-10-01 Impact factor: 21.405
Authors: Lisa J Meltzer; Petrina Wong; Sarah N Biggs; Joel Traylor; Ji Young Kim; Rakesh Bhattacharjee; Indra Narang; Carole L Marcus Journal: Sleep Date: 2016-06-01 Impact factor: 5.849