G Michas1, G Alevetsovitis1, I Andrikou1, S Tsimiklis1, E Vryonis2. 1. Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece. 2. Department of Internal Medicine, General Hospital of Kalamata, Kalamata, Greece ; North Middlesex University Hospital NHS Trust, London, UK.
Abstract
BACKGROUND/AIM: Viral infections have been frequently associated with subacute (De Quervain) thyroiditis and autoimmune thyroid diseases. In the present case report we document a rare case of De Quervain thyroiditis in the course of H1N1 influenza infection. DESCRIPTION OF THE CASE: A 17-year-old previously healthy female that was treated in the General Hospital of Kalamata developed an influenza-like syndrome that was accompanied by palpitations, thyroid enlargement, and increased C-reactive protein. Polymerase chain reaction assay confirmed the diagnosis of H1N1 virus infection. Serum thyroid-stimulating hormone was suppressed to zero while the levels of free thyroxine and triiodothyronine were increased. The patient was treated with non-steroidal anti-inflammatory drugs and thyroid function was gradually restored without evolving to a hypothyroid phase. CONCLUSION: To our knowledge this is the second case described in the literature of De Quervain thyroiditis associated with H1N1 influenza infection.
BACKGROUND/AIM: Viral infections have been frequently associated with subacute (De Quervain) thyroiditis and autoimmune thyroid diseases. In the present case report we document a rare case of De Quervain thyroiditis in the course of H1N1influenza infection. DESCRIPTION OF THE CASE: A 17-year-old previously healthy female that was treated in the General Hospital of Kalamata developed an influenza-like syndrome that was accompanied by palpitations, thyroid enlargement, and increased C-reactive protein. Polymerase chain reaction assay confirmed the diagnosis of H1N1 virus infection. Serum thyroid-stimulating hormone was suppressed to zero while the levels of free thyroxine and triiodothyronine were increased. The patient was treated with non-steroidal anti-inflammatory drugs and thyroid function was gradually restored without evolving to a hypothyroid phase. CONCLUSION: To our knowledge this is the second case described in the literature of De Quervain thyroiditis associated with H1N1influenza infection.
Authors: Rohit Ranganath; Manish A Shaha; Bin Xu; Jocelyn Migliacci; Ronald Ghossein; Ashok R Shaha Journal: Am J Otolaryngol Date: 2016-08-18 Impact factor: 1.808