Literature DB >> 25123270

Caveolin-1 in oral squamous cell carcinoma microenvironment: an overview.

Samapika Routray1.   

Abstract

Caveolin-1 plays an important role in the pathogenesis of oncogenic cell transformation, tumorigenesis, and metastasis. Increased expression of caveolin-1 in an array of tumors has confirmed its value in prognosis. It has been established that oxidative stress is the main cause for loss of stromal caveolin-1 via autophagy in the tumor microenvironment. In this overview, we attempt to abridge the relationship between caveolin-1 and oral squamous cell carcinoma, taking all the established theories into consideration.

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Year:  2014        PMID: 25123270     DOI: 10.1007/s13277-014-2482-z

Source DB:  PubMed          Journal:  Tumour Biol        ISSN: 1010-4283


  79 in total

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