| Literature DB >> 25123270 |
Abstract
Caveolin-1 plays an important role in the pathogenesis of oncogenic cell transformation, tumorigenesis, and metastasis. Increased expression of caveolin-1 in an array of tumors has confirmed its value in prognosis. It has been established that oxidative stress is the main cause for loss of stromal caveolin-1 via autophagy in the tumor microenvironment. In this overview, we attempt to abridge the relationship between caveolin-1 and oral squamous cell carcinoma, taking all the established theories into consideration.Entities:
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Year: 2014 PMID: 25123270 DOI: 10.1007/s13277-014-2482-z
Source DB: PubMed Journal: Tumour Biol ISSN: 1010-4283