| Literature DB >> 25123102 |
Edson Z Martinez1, Jorge A Achcar2.
Abstract
The cure fraction models have been widely used to analyze survival data in which a proportion of the individuals is not susceptible to the event of interest. In this article, we introduce a bivariate model for survival data with a cure fraction based on the three-parameter generalized Lindley distribution. The joint distribution of the survival times is obtained by using copula functions. We consider three types of copula function models, the Farlie-Gumbel-Morgenstern (FGM), Clayton and Gumbel-Barnett copulas. The model is implemented under a Bayesian framework, where the parameter estimation is based on Markov Chain Monte Carlo (MCMC) techniques. To illustrate the utility of the model, we consider an application to a real data set related to an invasive cervical cancer study.Entities:
Keywords: Bayesian analysis; Copula function; Cure fraction model; Lindley distribution; Survival analysis
Mesh:
Year: 2014 PMID: 25123102 DOI: 10.1016/j.cmpb.2014.07.011
Source DB: PubMed Journal: Comput Methods Programs Biomed ISSN: 0169-2607 Impact factor: 5.428