Literature DB >> 25121033

Pregnancy with gilbert syndrome - a case report.

Mini Mohan1, Lakshmi Sailaja P2, Peddireddy Vijaya Narasimha Reddy3.   

Abstract

A primigravida presented to us at 32 weeks of gestation with vomiting, myalgia and jaundice. On examination she had icterus, she was dehydrated, uterus was corresponding to dates and the fetal heart rate was good. On evaluation, all the investigations were normal except mild unconjugated hyperbilirubinaemia and hypoglycaemia. Based on the above findings we derived at a diagnosis of Gilbert syndrome. Dehydration due to vomiting aggravated her jaundice. On correcting her dehydration jaundice resolved, patient improved symptomatically and was discharged two days later. She was later admitted at term and underwent emergency caesarian section in view of fetal distress. Mother and baby were fine postoperatively and was discharged on the fifth postoperative day Gilbert syndrome is rare in obstetric practice. Virtually all patients have decreased activity of Uridine diphosphate glucuronosyl transferase (UDPGT). The case is reported due to its rarity.

Entities:  

Keywords:  Hyperbilirubinaemia; UDP Glucoronyltransferase

Year:  2014        PMID: 25121033      PMCID: PMC4129268          DOI: 10.7860/JCDR/2014/9327.4426

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  4 in total

1.  Gilbert's syndrome is not associated with HELLP syndrome.

Authors:  P L Zusterzeel; R te Morsche; M T Raijmakers; W H Peters; E A Steegers
Journal:  BJOG       Date:  2001-09       Impact factor: 6.531

2.  Hyperbilirubinemia, augmentation of endothelial function, and decrease in oxidative stress in Gilbert syndrome.

Authors:  Tatsuya Maruhashi; Junko Soga; Noritaka Fujimura; Naomi Idei; Shinsuke Mikami; Yumiko Iwamoto; Masato Kajikawa; Takeshi Matsumoto; Yasuki Kihara; Kazuaki Chayama; Kensuke Noma; Ayumu Nakashima; Hirofumi Tomiyama; Bonpei Takase; Akira Yamashina; Yukihito Higashi
Journal:  Circulation       Date:  2012-07-06       Impact factor: 29.690

Review 3.  Inheritable and congenital hyperbilirubinemia. Models for the study of drug metabolism.

Authors:  I M Arias
Journal:  N Engl J Med       Date:  1971-12-16       Impact factor: 91.245

4.  Gilbert's syndrome and the risk of death: a population-based cohort study.

Authors:  Laura J Horsfall; Irwin Nazareth; Stephen P Pereira; Irene Petersen
Journal:  J Gastroenterol Hepatol       Date:  2013-10       Impact factor: 4.029

  4 in total
  2 in total

1.  Gilbert's Syndrome With Diabetes Mellitus.

Authors:  Liu Haixia; Ruiman Li
Journal:  Cureus       Date:  2021-07-22

2.  Scoliosis in a Patient With Gilbert Syndrome: A Case Report and Review of the Literature.

Authors:  Zheng Li; Jianxiong Shen; Jinqian Liang
Journal:  Medicine (Baltimore)       Date:  2015-11       Impact factor: 1.817

  2 in total

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