| Literature DB >> 25121028 |
K Bharathi1, Vs Ajay Chandrasekar2, G Hemanathan3, S Anuradha4.
Abstract
Myofibroblastoma is a rare benign mesenchymal tumour of the breast commonly reported in males. It is a spindle cell neoplasm exhibiting myofibroblastic differentiation with characteristic immunohistochemical staining. Herein, we present a case of myofibroblastoma in a premenopausal female which was mimicking like malignancy clinically. Lump was growing rapidly in size measuring 8 cm x 6 cm and stony hard in consistency. Mammogram showed a large homogeneous hyperdense lump suggestive of fibroadenoma, Hamartoma and fibromatosis. FNAC and trucut biopsy of mass could not be done due to stony hard consistency. Hence excision biopsy was done. Histopathological examination revealed the tumour as myofibroblastoma. Immunohistochemical staining for markers of myofibroblasts like CD-34 and Vimentin showed strong positivity. A negative expression for cytokeratin was noted. This case is presented for its rarity, unusual clinical presentation and stony hard consistency.Entities:
Keywords: Myofibroblastoma Mesenchymal tumours CD 34 Vimentin
Year: 2014 PMID: 25121028 PMCID: PMC4129326 DOI: 10.7860/JCDR/2014/8214.4519
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X