Literature DB >> 25117913

Oral administration of the AYA strain of Lactobacillus plantarum modulates expression of immunity-related genes in the murine Peyer's patch: a DNA microarray analysis.

Yosuke Kikuchi1, Tsudoi Toyoda, Tomoko Ishijima, Keiko Abe, Yuji Nakai, Shin-Ichi Fukudome.   

Abstract

We performed comprehensive transcriptome analysis of Peyer's patches to elucidate the effects of oral administration of Lactobacillus plantarum strain AYA in mice. Using microarray analysis, we identified 124 upregulated and 144 downregulated genes for four weeks after the start of dietary supplementation with AYA. Gene Ontology analysis revealed that the genes for immune function were enriched in the upregulated gene set.

Entities:  

Keywords:  DNA microarray; Lactobacillus plantarum AYA; Peyer’s patch; immune function; mouse

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Year:  2014        PMID： 25117913     DOI： 10.1080/09168451.2014.940829

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  1 in total

1.  In vivo dose response and in vitro mechanistic analysis of enhanced immunoglobulin A production by Lactobacillus plantarum AYA.

Authors:  Yosuke Kikuchi; Hikaru Yoshida; Tasuku Ogita; Kimiko Okita; Shin-Ichi Fukudome; Takuya Suzuki; Soichi Tanabe
Journal:  Biosci Microbiota Food Health       Date:  2015-03-14
  1 in total

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