Literature DB >> 25115820

Epilepsy surgery in children: why, when and how?

Ajay Gupta1.   

Abstract

Epilepsy surgery is safe and effective treatment in children who fail to respond to antiepileptic medications. After failure of two appropriate antiepileptic medications, chances that the child will become seizure free with more or different medications is <5%, and she should be diagnosed with "refractory epilepsy". A consideration for surgical candidacy should be given to all children who fulfill the definition of refractory epilepsy. In appropriately selected children, epilepsy surgery offers a high chance of seizure freedom without incurring any new post-operative neurological deficits. No age is bar to epilepsy surgery. Even infants can safely have epilepsy surgery if they are surgical candidates. For most children, who are surgical candidates, a good history and physical examination, video EEG evaluation, and a high quality brain MRI are sufficient to make surgical decision. These tools are increasingly available all over the world. Better education of families, Pediatricians, Pediatric Neurologists and community care-givers is necessary to salvage children early from mortality and morbidity of untreated, sometimes life long, epilepsy.

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Year:  2014        PMID: 25115820     DOI: 10.1007/s12098-014-1541-1

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  47 in total

1.  A follow-up study of intractable seizures in childhood.

Authors:  P R Huttenlocher; R J Hapke
Journal:  Ann Neurol       Date:  1990-11       Impact factor: 10.422

2.  Anterior temporal lobectomy and medically refractory temporal lobe epilepsy of childhood.

Authors:  E M Mizrahi; P Kellaway; R G Grossman; P A Rutecki; D Armstrong; G Rettig; S Loewen
Journal:  Epilepsia       Date:  1990 May-Jun       Impact factor: 5.864

3.  Seizure symptomatology in infants with localization-related epilepsy.

Authors:  J N Acharya; E Wyllie; H O Lüders; P Kotagal; M Lancman; M Coelho
Journal:  Neurology       Date:  1997-01       Impact factor: 9.910

4.  The postoperative course and management of 106 hemidecortications.

Authors:  E H Kossoff; E P G Vining; P L Pyzik; S Kriegler; K-S Min; B S Carson; A M Avellino; J M Freeman
Journal:  Pediatr Neurosurg       Date:  2002-12       Impact factor: 1.162

5.  Developmental outcomes in children receiving resection surgery for medically intractable infantile spasms.

Authors:  R F Asarnow; C LoPresti; D Guthrie; T Elliott; V Cynn; W D Shields; D A Shewmon; R Sankar; W J Peacock
Journal:  Dev Med Child Neurol       Date:  1997-07       Impact factor: 5.449

Review 6.  Hemispherectomy for intractable unihemispheric epilepsy etiology vs outcome.

Authors:  E H Kossoff; E P G Vining; D J Pillas; P L Pyzik; A M Avellino; B S Carson; J M Freeman
Journal:  Neurology       Date:  2003-10-14       Impact factor: 9.910

7.  Surgery for intractable infantile spasms: neuroimaging perspectives.

Authors:  H T Chugani; D A Shewmon; W D Shields; R Sankar; Y Comair; H V Vinters; W J Peacock
Journal:  Epilepsia       Date:  1993 Jul-Aug       Impact factor: 5.864

Review 8.  Access to surgery for paediatric patients with medically refractory epilepsy: a systems analysis.

Authors:  Morgan E Lim; James M Bowen; O Carter Snead; Irene Elliott; Elizabeth Donner; Shelly K Weiss; Hiroshi Otsubo; Ayako Ochi; James Drake; James T Rutka; Andrew Worster; Robert B Hopkins; Ron Goeree; Jean-Eric Tarride
Journal:  Epilepsy Res       Date:  2013-09-02       Impact factor: 3.045

9.  Ictal SPECT in children with partial epilepsy due to focal cortical dysplasia.

Authors:  Ajay Gupta; Shankar Raja; Prakash Kotagal; Deepak Lachhwani; Elaine Wyllie; William B Bingaman
Journal:  Pediatr Neurol       Date:  2004-08       Impact factor: 3.372

10.  The role of hemispherectomy in the treatment of holohemispheric hemimegaloencephaly.

Authors:  J M Taha; K R Crone; T S Berger
Journal:  J Neurosurg       Date:  1994-07       Impact factor: 5.115

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  1 in total

1.  Editorial.

Authors:  Pratibha Singhi
Journal:  Indian J Pediatr       Date:  2014-08-08       Impact factor: 1.967

  1 in total

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