Literature DB >> 25115373

Simultaneous breast reconstruction and treatment of breast cancer-related upper arm lymphedema with lymphatic lower abdominal flap.

Ru Chen1, Lan Mu, Han Zhang, Minqiang Xin, Jie Luan, Dali Mu, Chunjun Liu, Kai Ji, Jiejie Hu, Jingjing Sun, Lixue Xuan, Yongying Rong, Liping Zheng, Peng Tang, Xiaojie Zhong, Huangfu Wu, Tianning Zou, Zhuangqing Yang, Corrine Becker.   

Abstract

BACKGROUND: This study was designed to introduce the key points about the transplantation of lower abdominal flap with vascularized lymph node and to evaluate the effect of breast restoration, breast reconstruction, and lymphatic transplantation to treat upper limb lymphedema after breast cancer surgery.
MATERIALS AND METHODS: The study was based on the retrospective study on 10 cases of postmastectomy lymphedema during January 2008 to March 2011. All patients, aged 36 to 50 years, have had one-side upper-limb lymphedema for 3 to 5 years. Six patients had accepted radiotherapy. Four patients had a diagnosis of severe lymphedema, and 2 patients had moderate lymphedema. The isotope radiography before the operation showed obstruction of lymphatic return, and the multidetector computed tomography that followed delivered a clear picture of the abdominal flap blood supply and the blood vessels in the breasts. During the operation, the scar contracture of the axilla was completely relaxed, and all patients accepted abdominal transplantation of lower abdominal flap with vascularized lymph node. After the operation, the elastic bandages were applied for one year as an adjuvant therapy. The follow-up visits were conducted 1, 3, 6, and 12 months after the surgery. The measurement indexes included mid-upper arm circumference, clinical symptoms, and lymphoscintigraphy.
RESULTS: All flaps worked well. One patient was found to have delayed wound healing; one patient saw no obvious improvement in lymphedema; 7 patients with lymphedema were relieved with apparent improvement in the affected limbs' mean perimeter and clinical symptoms; one patient recovered; and another patient was lost to follow-up. The mean reduction was 2.122±2.331 cm, and the reduction of the lymphedematous limb was statistically significant between the preoperative and 12-month postoperative groups (P<0.05). The results were good in 4 patients and excellent in one patient.
CONCLUSIONS: The transplantation of abdominal flap with vascularized lymph node and breast reconstruction, accompanied by the treatment to upper limb lymphedema and using elastic bandages as an adjuvant therapy, is considered to be an effective method to restore the configuration and function of breasts. Long-term follow-up visits are undergoing, especially the lymphoscintigraphy, 2 years after the operation.

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Mesh:

Year:  2014        PMID: 25115373     DOI: 10.1097/SAP.0000000000000322

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  7 in total

Review 1.  Lymph node transfer combined with deep inferior epigastric perforators and transverse rectus abdominis myocutaneous procedures: a systematic review.

Authors:  Antonio J Forte; Gabriela Cinotto; Daniel Boczar; Maria T Huayllani; Xiaona Lu; Oscar J Manrique; Sarah A McLaughlin
Journal:  Gland Surg       Date:  2020-04

Review 2.  Combined deep inferior epigastric artery perforator flap with vascularized groin lymph node transplant for treatment of breast cancer-related lymphedema.

Authors:  Mark V Schaverien; Edward I Chang
Journal:  Gland Surg       Date:  2021-01

3.  Lessons Learnt from an 11-year Experience with Lymphatic Surgery and a Systematic Review of Reported Complications: Technical Considerations to Reduce Morbidity.

Authors:  Pedro Ciudad; Joseph M Escandón; Oscar J Manrique; Valeria P Bustos
Journal:  Arch Plast Surg       Date:  2022-04-06

Review 4.  Combining Autologous Breast Reconstruction and Vascularized Lymph Node Transfer.

Authors:  Edward I Chang; Jaume Masià; Mark L Smith
Journal:  Semin Plast Surg       Date:  2018-04-09       Impact factor: 2.314

5.  Combined microvascular breast and lymphatic reconstruction with deep inferior epigastric perforator flap and gastroepiploic vascularized lymph node transfer for postmastectomy lymphedema patients.

Authors:  Pedro Ciudad; Oscar J Manrique; Samyd S Bustos; Maria I Vargas; César Reynaga; Mouchammed Agko; Tony C T Huang; Eduardo Figueroa Benites; Horacio F Mayer; Antonio J Forte
Journal:  Gland Surg       Date:  2020-04

6.  Effect of cryopreservation on lymph node fragment regeneration after autologous transplantation in the minipig model.

Authors:  Catarina Hadamitzky; Hanes Perić; Sebastian J Theobald; Klaus Friedrich Gratz; Hendrik Spohr; Reinhard Pabst; Peter M Vogt
Journal:  Innov Surg Sci       Date:  2018-04-20

7.  Simultaneous Lymphatic Superficial Circumflex Iliac Artery Perforator Flap Transfer from the Zone 4 Region in Autologous Breast Reconstruction Using the Deep Inferior Epigastric Artery Perforator Flap: A Proof-of-Concept Study.

Authors:  Hidehiko Yoshimatsu; Ryo Karakawa; Yuma Fuse; Tomoyuki Yano
Journal:  J Clin Med       Date:  2022-01-21       Impact factor: 4.241

  7 in total

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