Literature DB >> 25114878

Iodophilic synchronous phalangeal and choroidal metastasis from follicular thyroid carcinoma: a case report and review.

Darshan Patil1, Abhay Kumaraswamy Kattepur1, Srinivas Kodaganur Gopinath1, Shivanand Swamy1, Amarendra Shankarappa1, Gopinath Kodaganur Srinivasachar1.   

Abstract

BACKGROUND: Follicular thyroid cancers constitute 15-20% of all thyroid tumors. The usual mode of dissemination is via the hematogenous route. The most common sites of distant metastasis are to the lungs and bones.
OBJECTIVE: A case is presented to demonstrate the unusual presentation of follicular cancer with synchronous digital (distal phalanx of the little finger) and choroidal metastasis that was responsive to radioiodine treatment. CASE REPORT: A 54-year-old female presented with swelling over the terminal part of the left little finger with thyromegaly. Investigations revealed metastasis from follicular thyroid cancer to the little finger along with pulmonary metastases. She underwent total thyroidectomy with central compartment clearance followed by (131)I therapy. Subsequent follow-up demonstrated complete regression of the digital metastasis and partial regression of the choroidal metastasis which was evaluated after the radioiodine scan that picked up the choroidal metastasis.
CONCLUSION: Follicular thyroid cancers can rarely spread to unusual sites like the digits and choroid. This report highlights the synchronous presentation of digital and choroidal metastasis which responded to (131)I therapy.

Entities:  

Keywords:  Choroid; Follicular thyroid cancer; Metastasis; Phalanx; Radioiodine

Year:  2014        PMID: 25114878      PMCID: PMC4109503          DOI: 10.1159/000360533

Source DB:  PubMed          Journal:  Eur Thyroid J        ISSN: 2235-0640


  10 in total

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9.  Papillary thyroid carcinoma with an uncommon spread of hematogenous metastases to the choroid and the skin.

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10.  An atypical metastasis of follicular-type adenocarcinoma of the thyroid gland to thumb.

Authors:  Gazi Huri
Journal:  Case Rep Orthop       Date:  2011-12-29
  10 in total
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  2 in total

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