Literature DB >> 25114474

Steatohepatitic hepatocellular carcinoma-a case report with literature review.

Nalini Gupta1, Archana Rastogi2, Chhagan Bihari2.   

Abstract

We report a case of a 65 year old male who presented with complaints of pain right upper abdomen for past 3 months. He was a known diabetic and hypertensive. On evaluation he was found to have space occupying lesion in the right lobe of the liver. USG Guided FNC done showed a Hepatocellular Carcinoma with predominant steatosis. He underwent Right Hepetectomy for the same and Histopathological examination revealed a Steatohepatitic Hepatocellular Carcinoma with background liver showing minimal steatosis and no significant fibrosis. This case is reported to provide better insight into the understanding of pathophysiology of metabolic syndrome as an etiological agent for development of HCC.

Entities:  

Keywords:  Hepatocellular Carcinoma (HCC); Metabolic syndrome; Non alchohalic fatty liver disease (NAFLD); Non alchohalic steatohepatitis (NASH); Steatohepatitic Hepatocellular Carcinoma (SH-HCC)

Year:  2014        PMID: 25114474      PMCID: PMC4116540          DOI: 10.1007/s13193-014-0297-4

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  6 in total

1.  Steatohepatitic hepatocellular carcinoma (SH-HCC): a distinctive histological variant of HCC in hepatitis C virus-related cirrhosis with associated NAFLD/NASH.

Authors:  Marcela Salomao; Woojin M Yu; Robert S Brown; Jean C Emond; Jay H Lefkowitch
Journal:  Am J Surg Pathol       Date:  2010-11       Impact factor: 6.394

2.  The steatohepatitic variant of hepatocellular carcinoma and its association with underlying steatohepatitis.

Authors:  Marcela Salomao; Helen Remotti; Roger Vaughan; Abby B Siegel; Jay H Lefkowitch; Roger Klein Moreira
Journal:  Hum Pathol       Date:  2011-10-20       Impact factor: 3.466

3.  Steatohepatitic hepatocellular carcinoma, a morphologic indicator of associated metabolic risk factors: a study from India.

Authors:  Deepali Jain; Nabeen C Nayak; Vinay Kumaran; Sanjiv Saigal
Journal:  Arch Pathol Lab Med       Date:  2013-07       Impact factor: 5.534

Review 4.  Epidemiology of hepatocellular carcinoma.

Authors:  F Xavier Bosch; Josepa Ribes; Ramon Cléries; Mireia Díaz
Journal:  Clin Liver Dis       Date:  2005-05       Impact factor: 6.126

Review 5.  Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace.

Authors:  György Baffy; Elizabeth M Brunt; Stephen H Caldwell
Journal:  J Hepatol       Date:  2012-02-09       Impact factor: 25.083

Review 6.  Hepatocellular carcinoma: epidemiology and molecular carcinogenesis.

Authors:  Hashem B El-Serag; K Lenhard Rudolph
Journal:  Gastroenterology       Date:  2007-06       Impact factor: 22.682

  6 in total
  1 in total

1.  Different Nodules Identified during Liver Explant Gross Examination: Relevance and Need for Sectioning-Experience from India.

Authors:  Nalini Bansal; Vivek Vij; Mukul Rastogi
Journal:  Int J Hepatol       Date:  2016-06-22
  1 in total

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