Kadri Suija1, Marja Kerkelä2, Ulla Rajala2, Jari Jokelainen3, Mauri Laakso3, Pirjo Härkönen4, Sirkka Keinänen-Kiukaanniemi3, Markku Timonen4. 1. Institute of Health Sciences, University of Oulu, Oulu, Finland Oulu Mentalcare Oy, Oulu, Finland kadri.suija@ut.ee. 2. Institute of Health Sciences, University of Oulu, Oulu, Finland. 3. Institute of Health Sciences, University of Oulu, Oulu, Finland Unit of Primary Health Care, Oulu University Hospital, Oulu, Finland. 4. Institute of Health Sciences, University of Oulu, Oulu, Finland Oulu Mentalcare Oy, Oulu, Finland.
Abstract
AIMS: The aim of this study was to investigate the association between erectile dysfunction and depressive symptoms and testosterone levels among middle-aged men at the community level. METHODS: The study population consisted of 614 men born in 1945 and living in the city of Oulu, Finland. Erectile dysfunction was assessed by the erectile function domain of the International Index of Erectile Function questionnaire and depressive symptoms by the Beck Depression Inventory. Blood samples were collected to measure testosterone and sex hormone-binding globulin level. RESULTS: After adjusting for confounders, erectile dysfunction was statistically significantly associated with depressive symptoms (risk ratio (RR) 1.66, 95% confidence interval (95% CI) 1.29-2.15), as well as with obesity (RR 1.72, 95% CI 1.12-2.62). Neither total nor free testosterone level was associated with erectile dysfunction among our study group. CONCLUSIONS: Depressive symptoms rather than testosterone levels should be taken into consideration while treating middle-aged men with erectile problems at the community level.
AIMS: The aim of this study was to investigate the association between erectile dysfunction and depressive symptoms and testosterone levels among middle-aged men at the community level. METHODS: The study population consisted of 614 men born in 1945 and living in the city of Oulu, Finland. Erectile dysfunction was assessed by the erectile function domain of the International Index of Erectile Function questionnaire and depressive symptoms by the Beck Depression Inventory. Blood samples were collected to measure testosterone and sex hormone-binding globulin level. RESULTS: After adjusting for confounders, erectile dysfunction was statistically significantly associated with depressive symptoms (risk ratio (RR) 1.66, 95% confidence interval (95% CI) 1.29-2.15), as well as with obesity (RR 1.72, 95% CI 1.12-2.62). Neither total nor free testosterone level was associated with erectile dysfunction among our study group. CONCLUSIONS:Depressive symptoms rather than testosterone levels should be taken into consideration while treating middle-aged men with erectile problems at the community level.
Authors: Jouko Saramies; Markku Koiranen; Juha Auvinen; Hannu Uusitalo; Esko Hussi; Sebastian Becker; Sirkka Keinänen-Kiukaanniemi; Jaakko Tuomilehto; Kadri Suija Journal: J Clin Med Date: 2022-04-12 Impact factor: 4.964
Authors: Nigel Field; Philip Prah; Catherine H Mercer; Greta Rait; Michael King; Jackie A Cassell; Clare Tanton; Laura Heath; Kirstin R Mitchell; Soazig Clifton; Jessica Datta; Kaye Wellings; Anne M Johnson; Pam Sonnenberg Journal: BMJ Open Date: 2016-03-23 Impact factor: 2.692